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Context Info
Confidence 0.36
First Reported 1992
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 1.17
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

enzyme regulator activity (PSMD3) cytosol (PSMD3) nucleoplasm (PSMD3)
small molecule metabolic process (PSMD3) cellular nitrogen compound metabolic process (PSMD3)
Anatomy Link Frequency
internal 1
parasympathetic 1
PSMD3 (Homo sapiens)
Pain Link Frequency Relevance Heat
potassium channel 6 79.12 Quite High
Pain 3 75.32 Quite High
nud 1 71.52 Quite High
addiction 8 64.44 Quite High
Calcium channel 1 34.52 Quite Low
sodium channel 10 32.16 Quite Low
antagonist 3 5.00 Very Low Very Low Very Low
Glutamate 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

1 99.98 Very High Very High Very High
Alzheimer's Dementia 91 97.64 Very High Very High Very High
Skin Cancer 52 86.08 High High
Pain 2 75.32 Quite High
Dyspepsia 1 71.52 Quite High
Cancer 20 62.96 Quite High
Apoptosis 27 50.00 Quite Low
Death 8 8.92 Low Low
Disease 16 5.00 Very Low Very Low Very Low
American Trypanosomiasis 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The sensation of rectal distension travels with the parasympathetic system to S2, S3 and S4.
S3 Binding (travels) of in parasympathetic
1) Confidence 0.36 Published 1992 Journal Baillieres Clin. Gastroenterol. Section Abstract Doc Link 1586768 Disease Relevance 0.21 Pain Relevance 0.17
These results suggested that compounds S3–S6 have a much weaker anti-proliferative effect to be further tested in in vivo assays.
S3 Binding (compounds) of
2) Confidence 0.09 Published 2007 Journal Mol Cancer Section Body Doc Link PMC1785384 Disease Relevance 0.33 Pain Relevance 0.03
It has been suggested that: (i) voltage-gating domains have a large amount of internal flexibility compared with the pore domains, (ii) the V-paddle is situated on the periphery of the V-domain with some cationic sidechains interacting with anionic elements of adjacent subunits S1, S2 and S3; (iii) S2 and S3 are situated more proximal than V-paddle to the P-domain, and (iv) some S4 arginine residues interact in a critical fashion with the lipid membrane [2], [4], [16], [17], [18], [19], [20].
S3 Binding (interacting) of in internal
3) Confidence 0.03 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2766034 Disease Relevance 0 Pain Relevance 0.07
However, five short-acting GnRH analogs, i.e., S3, S4, S6, S10, and S11, bind CR, showing that some short-acting GnRH-analogs are able to form amyloids after prolonged incubation (see also below).
S3 Binding (bind) of
4) Confidence 0.02 Published 2008 Journal PLoS Biology Section Body Doc Link PMC2225439 Disease Relevance 0.53 Pain Relevance 0
Four subsites on the acyl side of the cleaved peptide bond, named S4, S3, S2, and S1, bind the peptide amino acids P4, P3, P2, and P1.
S3 Binding (bind) of
5) Confidence 0.02 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2867933 Disease Relevance 0 Pain Relevance 0

General Comments

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