INT116901

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Context Info
Confidence 0.36
First Reported 2004
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.40
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (PRF1) extracellular region (PRF1) cytoplasmic membrane-bounded vesicle (PRF1)
plasma membrane (PRF1)
PRF1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 3 10.00 Low Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Paracetamol 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 7 86.36 High High
Cv General 3 Under Development 1 78.80 Quite High
Cancer 9 78.40 Quite High
Cardiovascular Disease 3 77.76 Quite High
Diabetes Mellitus 12 75.52 Quite High
Shock 4 50.00 Quite Low
Acute Coronary Syndrome 2 50.00 Quite Low
Adhesions 5 29.92 Quite Low
Disease 4 12.32 Low Low
Nicotine Addiction 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Despite substantial variability, there was a trend toward increased transcript abundance for PRF1, IL2RB, and KIR3DL1 with increasing urinary arsenic concentration.
Positive_regulation (increased) of Transcription (abundance) of PRF1
1) Confidence 0.36 Published 2008 Journal Environ Health Perspect Section Body Doc Link PMC2290973 Disease Relevance 0.32 Pain Relevance 0
CD4+CD28null cells were separated by flow cytometry and assessed for antigen recognition using upregulation of interferon-gamma and perforin mRNA transcription as criteria for activation.
Positive_regulation (upregulation) of Transcription (transcription) of perforin mRNA
2) Confidence 0.01 Published 2004 Journal Circulation Section Body Doc Link 14993140 Disease Relevance 0.08 Pain Relevance 0

General Comments

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