INT116930

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Context Info
Confidence 0.28
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.35
Pain Relevance 0.93

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transducer activity (OPRK1, PTK2) plasma membrane (OPRK1, PTK2) extracellular matrix organization (PTK2)
embryo development (PTK2) microtubule organizing center (PTK2) cytoplasm (PTK2)
OPRK1 (Homo sapiens)
PTK2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Kappa opioid receptor 16 100.00 Very High Very High Very High
agonist 4 84.32 Quite High
opioid receptor 2 58.40 Quite High
Opioid 2 53.76 Quite High
Disease Link Frequency Relevance Heat
Adhesions 4 98.44 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Consistently, activated kappa-opioid receptor induced Src stimulation and FAK autophosphorylation and promoted the formation of Src-FAK complex.
kappa-opioid receptor Positive_regulation (promoted) of Src-FAK Binding (complex) of associated with kappa opioid receptor
1) Confidence 0.28 Published 2004 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 14996948 Disease Relevance 0.17 Pain Relevance 0.47
Consistently, activated kappa-opioid receptor induced Src stimulation and FAK autophosphorylation and promoted the formation of Src-FAK complex.
kappa-opioid receptor Positive_regulation (promoted) of Src-FAK Binding (complex) of associated with kappa opioid receptor
2) Confidence 0.28 Published 2004 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 14996948 Disease Relevance 0.17 Pain Relevance 0.47

General Comments

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