INT116932

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Context Info
Confidence 0.35
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.17
Pain Relevance 0.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (PTK2, MAPK8) cytosol (PTK2, MAPK8) nucleus (PTK2, MAPK8)
nucleoplasm (MAPK8) mitochondrion (MAPK8) extracellular matrix organization (PTK2)
PTK2 (Homo sapiens)
MAPK8 (Homo sapiens)
Pain Link Frequency Relevance Heat
Kappa opioid receptor 8 100.00 Very High Very High Very High
agonist 2 72.64 Quite High
opioid receptor 1 65.04 Quite High
Opioid 1 60.40 Quite High
Disease Link Frequency Relevance Heat
Adhesions 2 100.00 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, the JNK activation in response to kappa-opioid receptor was suppressed by an autophosphorylation-resistant mutant of focal adhesion kinase (FAK).
FAK Negative_regulation (suppressed) of Positive_regulation (activation) of JNK associated with kappa opioid receptor and adhesions
1) Confidence 0.35 Published 2004 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 14996948 Disease Relevance 0.17 Pain Relevance 0.48

General Comments

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