INT117080

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Context Info
Confidence 0.42
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 6
Total Number 6
Disease Relevance 7.23
Pain Relevance 3.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Csrp1)
Anatomy Link Frequency
B-cell 1
Csrp1 (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 76 100.00 Very High Very High Very High
Fibrositis 63 99.00 Very High Very High Very High
Etanercept 22 98.76 Very High Very High Very High
rheumatoid arthritis 35 98.60 Very High Very High Very High
Inflammation 8 97.32 Very High Very High Very High
pain pelvic 1 92.00 High High
Lasting pain 15 90.24 High High
cytokine 3 89.84 High High
anakinra 2 84.20 Quite High
abatacept 6 83.72 Quite High
Disease Link Frequency Relevance Heat
Pain 89 100.00 Very High Very High Very High
Weight Loss 1 99.92 Very High Very High Very High
Communicable Diseases 7 99.08 Very High Very High Very High
Fibromyalgia 63 99.00 Very High Very High Very High
Rheumatoid Arthritis 36 98.60 Very High Very High Very High
Disease 30 98.24 Very High Very High Very High
Arthralgia 2 97.92 Very High Very High Very High
INFLAMMATION 8 97.32 Very High Very High Very High
Synovitis 4 97.04 Very High Very High Very High
Tendinitis And Tenosynovitis 1 96.16 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Elevation of CRP and sedimentation rate as well as leucocytosis are the most important laboratory findings.
Localization (rate) of CRP
1) Confidence 0.42 Published 2004 Journal Orthopade Section Abstract Doc Link 15007553 Disease Relevance 0.42 Pain Relevance 0.12
CRP and ESR are elevated.
Localization (elevated) of CRP
2) Confidence 0.41 Published 2009 Journal Z Rheumatol Section Abstract Doc Link 19585133 Disease Relevance 1.93 Pain Relevance 0.23
Following treatment, as CRP and VAS decreased, vascular function improved for both ACh (P<0.00001) and SNP (P=0.001), this improvement being significantly greater for ACh (P<0.001).
Localization (decreased) of CRP
3) Confidence 0.19 Published 2007 Journal Atherosclerosis Section Abstract Doc Link 16806231 Disease Relevance 1.19 Pain Relevance 0.68
The risk of inpatient hospital care due to infectious diseases was significantly increased both in subjects reporting CRP (OR 1.6; p = 0.044) and CWP (OR 2.0; p = 0.011).
Localization (reporting) of CRP associated with pain, communicable diseases and fibrositis
4) Confidence 0.19 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2903507 Disease Relevance 2.00 Pain Relevance 1.23
Her arthralgia disappeared with a few days after treatment with prednisolone (10 mg per day) was started, and ESR and CRP were normalized.
Localization (normalized) of CRP associated with arthralgia
5) Confidence 0.12 Published 2009 Journal Nippon Ronen Igakkai Zasshi Section Abstract Doc Link 19491524 Disease Relevance 1.19 Pain Relevance 0.23
The combination of the B-cell depleting antiCD20 antibody rituximab and etanercept in our two patients showed a clinically relevant improvement measured by DAS28, CRP and radiological assessment leading to low disease activity in both patients up to 45 months after initiation of combination therapy.
Localization (measured) of CRP in B-cell associated with disease and etanercept
6) Confidence 0.02 Published 2009 Journal The Open Rheumatology Journal Section Body Doc Link PMC2684711 Disease Relevance 0.50 Pain Relevance 0.61

General Comments

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