INT117083

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Context Info
Confidence 0.60
First Reported 2003
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 6
Disease Relevance 9.10
Pain Relevance 0.80

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (RTEL1) helicase activity (RTEL1) DNA binding (RTEL1)
Anatomy Link Frequency
articular 2
B-cell 2
joint 1
RTEL1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Arthritis 78 93.40 High High
abdominal pain 1 92.00 High High
imagery 15 90.00 High High
Pain 16 79.04 Quite High
alcohol 6 67.92 Quite High
backache 6 39.00 Quite Low
Inflammation 12 38.60 Quite Low
rheumatoid arthritis 3 30.48 Quite Low
vincristine 6 25.00 Low Low
positron emission tomography 12 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Lymphatic System Cancer 142 100.00 Very High Very High Very High
Hodgkin's Disease 55 100.00 Very High Very High Very High
Leukemia 2 100.00 Very High Very High Very High
Recurrence 9 99.24 Very High Very High Very High
Cancer 38 98.26 Very High Very High Very High
Acute Myeloid Leukemia 26 97.74 Very High Very High Very High
Myelodysplastic Syndromes 28 97.66 Very High Very High Very High
Asthenia 1 94.88 High High
Arthritis 75 93.40 High High
Abdominal Pain 1 92.00 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The adrenal localization of a primary non-Hodgkin lymphoma (NHL) is rare.
Localization (localization) of NHL associated with hodgkin's disease
1) Confidence 0.60 Published 2003 Journal J. Endocrinol. Invest. Section Abstract Doc Link 15008252 Disease Relevance 0.63 Pain Relevance 0.17
On top of this, a computed tomography (CT) scan of the abdomen revealed regression of the mesenteric NHL-tumor mass after chemotherapy, which means that in the case of any presumed intra-articular localization of NHL, one would expect relapse of joint involvement in the course of chemotherapy instead of progression.
Localization (localization) of NHL in articular associated with cancer, hodgkin's disease and recurrence
2) Confidence 0.13 Published 2007 Journal Clin Rheumatol Section Body Doc Link PMC2262146 Disease Relevance 1.59 Pain Relevance 0.21
Furthermore intra-articular localization of NHL was considered.
Localization (localization) of NHL in articular associated with hodgkin's disease
3) Confidence 0.11 Published 2007 Journal Clin Rheumatol Section Body Doc Link PMC2262146 Disease Relevance 1.74 Pain Relevance 0.21
However, both primary and secondary intra-articular localization of NHL is very rare [4], and the fact that more than one joint is afflicted in this patient makes it even more unlikely.
Localization (localization) of NHL in joint associated with hodgkin's disease
4) Confidence 0.11 Published 2007 Journal Clin Rheumatol Section Body Doc Link PMC2262146 Disease Relevance 1.74 Pain Relevance 0.21
In a multicenter, single-arm trial, 47 patients with relapsed or refractory B-cell NHL were treated with 131I-TST.
Localization (treated) of NHL in B-cell associated with lymphatic system cancer
5) Confidence 0.04 Published 2009 Journal OncoTargets and therapy Section Body Doc Link PMC2886324 Disease Relevance 1.24 Pain Relevance 0
The annualized incidence of AML/MDS was 1.6%/year which is similar to that of patients treated with multiple chemotherapy regimens.29 In a study of 76 patients treated with upfront 131I-TST monotherapy for follicular NHL, no patients developed MDS/AML with a median follow-up of 7.93 years.30 Distinguishing the attributable risk of MDS/AML to chemotherapy or 131I-TST is difficult, although it appears that 131I-TST does not significantly increase the risk of leukemia.29

131I-TST in relapsed B-cell NHL

Localization (risk) of NHL in B-cell associated with leukemia, lymphatic system cancer, myelodysplastic syndromes and acute myeloid leukemia
6) Confidence 0.04 Published 2009 Journal OncoTargets and therapy Section Body Doc Link PMC2886324 Disease Relevance 2.16 Pain Relevance 0

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