INT11721

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Context Info
Confidence 0.61
First Reported 1990
Last Reported 2006
Negated 0
Speculated 0
Reported most in Title
Documents 3
Total Number 3
Disease Relevance 0.76
Pain Relevance 1.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
obsolete 1
brain 1
Srms (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Morphine 5 100.00 Very High Very High Very High
opiate 2 94.20 High High
Lasting pain 2 93.20 High High
fortral 1 85.76 High High
antagonist 1 77.68 Quite High
Glutamate receptor 1 72.88 Quite High
Pain 92 71.68 Quite High
backache 67 55.00 Quite High
visual analogue scale 3 51.52 Quite High
monoamine 1 42.76 Quite Low
Disease Link Frequency Relevance Heat
Pain 95 93.20 High High
Cancer 2 92.12 High High
Low Back Pain 69 55.00 Quite High
Affective Disorder 1 40.08 Quite Low
Sleep Disorders 1 39.28 Quite Low
Vomiting 1 38.32 Quite Low
Depression 1 37.68 Quite Low
Anxiety Disorder 1 36.40 Quite Low
Psychosis 1 35.52 Quite Low
Confusion 1 27.84 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The purpose of this double-blind crossover study was to determine whether a sustained-release morphine sulfate (SRMS) tablet given orally every 12 hours could adequately replace immediate-release morphine sulfate solution (IRMS) given orally every 4 hours in hospitalized patients with chronic pain from advanced cancer.
Localization (release) of SRMS associated with cancer, lasting pain and morphine
1) Confidence 0.61 Published 1992 Journal Am. J. Clin. Oncol. Section Abstract Doc Link 1590284 Disease Relevance 0.39 Pain Relevance 0.52
Stratford et al. argues convincingly that the proper analysis for this design would be either the area under ROC curve or Norman's Srepeat, and our inclusion of SRMs may therefore seem obsolete.
Localization (inclusion) of SRMs in obsolete
2) Confidence 0.06 Published 2006 Journal BMC Musculoskelet Disord Section Body Doc Link PMC1635558 Disease Relevance 0.37 Pain Relevance 0.37
Sigma binding sites in the brain; an emerging concept for multiple sites and their relevance for psychiatric disorders.
Localization (relevance) of sites in brain
3) Confidence 0.00 Published 1990 Journal Life Sci. Section Title Doc Link 2172677 Disease Relevance 0 Pain Relevance 0.34

General Comments

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