INT117210

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.48
First Reported 2004
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.82
Pain Relevance 1.91

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Hcn2) plasma membrane (Hcn2) transmembrane transport (Hcn2)
Anatomy Link Frequency
neurons 1
spinal cord 1
Hcn2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
hCN2 20 100.00 Very High Very High Very High
Calcitonin gene-related peptide 2 100.00 Very High Very High Very High
dorsal rhizotomy 2 99.84 Very High Very High Very High
Spinal cord 4 99.52 Very High Very High Very High
spinal dorsal horn 8 98.94 Very High Very High Very High
Dorsal horn 3 98.36 Very High Very High Very High
dorsal root ganglion 6 97.36 Very High Very High Very High
c fibre 2 80.80 Quite High
unmyelinated 1 80.44 Quite High
Adelta 2 79.72 Quite High
Disease Link Frequency Relevance Heat
Nociception 6 97.56 Very High Very High Very High
Ganglion Cysts 7 97.36 Very High Very High Very High
Overactive Bladder 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In double labelling immunohistochemical studies, we have also shown that HCN2 widely co-localizes with calcitonin gene-related peptide, but is almost completely segregated from isolectin-B4 binding, indicating that HCN2 is primarily expressed in peptidergic nociceptive primary afferents.
HCN2 Binding (binding) of associated with nociception, calcitonin gene-related peptide and hcn2
1) Confidence 0.48 Published 2004 Journal Eur. J. Neurosci. Section Abstract Doc Link 15016091 Disease Relevance 0.17 Pain Relevance 0.72
Using immunohistochemical methods, we have demonstrated that laminae I-IIo of the superficial spinal dorsal horn of the adult rat spinal cord show a strong punctate immunoreactivity for HCN2.
HCN2 Binding (immunoreactivity) of in spinal cord associated with spinal dorsal horn, hcn2 and spinal cord
2) Confidence 0.36 Published 2004 Journal Eur. J. Neurosci. Section Abstract Doc Link 15016091 Disease Relevance 0.14 Pain Relevance 0.61
Among HCN-1, HCN-2 and HCN-4 channel subtypes, positive staining with HCN-2 antibodies was found in the superficial dorsal horn of the spinal cord and small- and medium-sized unidentified DRG neurons.
HCN-2 Binding (staining) of in neurons associated with dorsal root ganglion, dorsal horn and spinal cord
3) Confidence 0.35 Published 2006 Journal Brain Res. Section Abstract Doc Link 16979600 Disease Relevance 0.51 Pain Relevance 0.59

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox