INT117217

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Context Info
Confidence 0.25
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.17
Pain Relevance 0.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Calca, Hcn2) intracellular (Calca) transmembrane transport (Hcn2)
cytoplasm (Calca) extracellular space (Calca) extracellular region (Calca)
Calca (Rattus norvegicus)
Hcn2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
hCN2 10 100.00 Very High Very High Very High
Calcitonin gene-related peptide 1 100.00 Very High Very High Very High
Dorsal horn 1 94.08 High High
dorsal rhizotomy 1 91.48 High High
Spinal cord 1 88.80 High High
spinal dorsal horn 4 87.64 High High
HCN1 1 68.28 Quite High
Pain 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Nociception 3 94.20 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In double labelling immunohistochemical studies, we have also shown that HCN2 widely co-localizes with calcitonin gene-related peptide, but is almost completely segregated from isolectin-B4 binding, indicating that HCN2 is primarily expressed in peptidergic nociceptive primary afferents.
calcitonin Binding (co-localizes) of HCN2 associated with nociception, calcitonin gene-related peptide and hcn2
1) Confidence 0.25 Published 2004 Journal Eur. J. Neurosci. Section Abstract Doc Link 15016091 Disease Relevance 0.17 Pain Relevance 0.68

General Comments

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