INT11730

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Context Info
Confidence 0.40
First Reported 1984
Last Reported 1992
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.60
Pain Relevance 0.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Mention Frequency
eye 1
IGG2B (Sus scrofa)
IGG2B (Sus scrofa)
Pain Term Frequency Confidence Heat
Multiple sclerosis 3 97.12 Very High Very High Very High
Central nervous system 1 94.04 High High
Neuritis 4 83.96 Quite High
Pain 3 42.80 Quite Low
Disease Term Frequency Confidence Heat
Hemolytic Anemia 2 99.20 Very High Very High Very High
Disease 2 98.52 Very High Very High Very High
Spherocytosis 1 97.96 Very High Very High Very High
Sickle Cell Anemia 4 97.76 Very High Very High Very High
Cancer 6 97.72 Very High Very High Very High
Demyelinating Disease 3 97.12 Very High Very High Very High
Optic Neuritis 4 83.96 Quite High
Sarcoma 1 58.88 Quite High
Adenocarcinoma 1 56.88 Quite High
Anaemia 1 44.80 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The percentage of cases with at least one altered CSF IgG parameter (IgG index, IgG synthesis/day and IgG oligoclonal bands) has been higher than that of cases with one or more altered neurophysiological tests, regardless of the apparently intact eye VEP.
IgG Binding (index) of IgG in eye
1) Confidence 0.40 Published 1987 Journal Acta Neurol. Scand. Section Abstract Doc Link 3577677 Disease Relevance 0.44 Pain Relevance 0.50
Although patients with hereditary spherocytosis, pyruvate kinase deficiency, and mechanical hemolytic anemias generally had normal concentrations of IgG bound to their red cells (less than 25 molecules IgG per red cell), we found that 39/62 (63%) patients with sickle cell anemia had elevated values.
IgG Binding (bound) of IgG associated with sickle cell anemia, spherocytosis and hemolytic anemia
2) Confidence 0.34 Published 1984 Journal Blood Section Abstract Doc Link 6733279 Disease Relevance 0.46 Pain Relevance 0
Protein A binds the Fc fragment of IgG 1, 2 and 4, and preferentially binds to IgG incorporated into immune complexes.
IgG Binding (binds) of IgG
3) Confidence 0.18 Published 1992 Journal Int. J. Clin. Lab. Res. Section Abstract Doc Link 1591370 Disease Relevance 0.71 Pain Relevance 0

General Comments

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