INT117316

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Context Info
Confidence 0.59
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 3.11
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (GZMA) extracellular region (GZMA) nucleus (GZMA)
Anatomy Link Frequency
plasma 1
GZMA (Homo sapiens)
Pain Link Frequency Relevance Heat
Angina 1 96.76 Very High Very High Very High
Potency 1 96.64 Very High Very High Very High
imagery 1 15.68 Low Low
Inflammation 4 13.00 Low Low
cytokine 14 7.60 Low Low
iatrogenic 4 5.00 Very Low Very Low Very Low
chemokine 4 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 59 99.74 Very High Very High Very High
Food Hypersensitivity 1 99.40 Very High Very High Very High
Sarcoma 195 99.30 Very High Very High Very High
Urticaria 2 99.28 Very High Very High Very High
Angina 1 96.76 Very High Very High Very High
Heart Rate Under Development 2 96.20 Very High Very High Very High
Anaphylaxis 8 94.80 High High
Acquired Immune Deficiency Syndrome Or Hiv Infection 125 94.44 High High
Contagious Ecthyma 61 93.52 High High
Airway Obstruction 2 90.04 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Serum tryptase is elevated less often in food allergy, and correlates poorly with plasma histamine level.
Positive_regulation (elevated) of Serum tryptase in plasma associated with food hypersensitivity
1) Confidence 0.59 Published 2004 Journal Novartis Found. Symp. Section Abstract Doc Link 15025394 Disease Relevance 1.59 Pain Relevance 0.10
Approaches to recruit CTLs to the tumor site and to facilitate the CTL functions at the tumor site would need to be developed to increase the therapeutic potency of the cancer vaccine.


Positive_regulation (facilitate) of CTL associated with cancer and potency
2) Confidence 0.01 Published 2010 Journal J Transl Med Section Body Doc Link PMC2949666 Disease Relevance 0.62 Pain Relevance 0.05
In one patient, whose KS had resolved under HAART therapy, CTL activity was restored.
Positive_regulation (restored) of CTL associated with sarcoma
3) Confidence 0.01 Published 2005 Journal Virol J Section Body Doc Link PMC1243244 Disease Relevance 0.90 Pain Relevance 0

General Comments

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