INT117345

Context Info Confidence 0.00 First Reported 2004 Last Reported 2004 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 1.05 Pain Relevance 0.18

AREG (Homo sapiens)

Pain Link Frequency Relevance Heat Cannabinoid receptor 1 90.32 Cannabinoid 3 75.00 Pain 1 64.76

Disease Link Frequency Relevance Heat Cancer 7 97.64 Necrosis 2 97.40 Lung Cancer 1 78.56 Glioblastoma 1 76.92 Apoptosis 2 69.04 Pain 1 64.76 Vomiting 2 64.36 Immunotherapy Of Cancer 1 63.12

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Depending on the cellular context, signal cross-communication was mediated by shedding of proAmphiregulin (proAR) and/or proHeparin-binding epidermal growth factor-like growth factor (proHB-EGF) by tumor necrosis factor alpha converting enzyme (TACE/ADAM17).

Negative_regulation (shedding) of proAmphiregulin Binding (proHeparin-binding) of associated with necrosis and cancer

1) Confidence 0.00 Published 2004 Journal Cancer Res. Section Abstract Doc Link 15026328 Disease Relevance 1.05 Pain Relevance 0.18

General Comments

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