INT117464

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Context Info
Confidence 0.39
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.31
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (TOP2B) nucleoplasm (TOP2B) nucleolus (TOP2B)
chromosome (TOP2B) nucleus (TOP2B) enzyme binding (TOP2B)
Anatomy Link Frequency
cleavage 2
TOP2B (Homo sapiens)
Pain Link Frequency Relevance Heat
Paracetamol 5 75.00 Quite High
Analgesic 2 66.20 Quite High
Disease Link Frequency Relevance Heat
Poisoning 3 87.68 High High
Leukemia 1 76.08 Quite High
Overdose 2 68.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
NAPQI strongly impaired the ability of topoisomerase IIalpha to reseal cleaved DNA molecules, suggesting that inhibition of DNA religation is the primary mechanism underlying cleavage enhancement.
Negative_regulation (impaired) of topoisomerase Binding (ability) of in cleavage
1) Confidence 0.39 Published 2004 Journal Biochemistry Section Abstract Doc Link 15035644 Disease Relevance 0.31 Pain Relevance 0.42

General Comments

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