INT117498

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Context Info
Confidence 0.18
First Reported 2004
Last Reported 2004
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.91
Pain Relevance 1.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (F2r) plasma membrane (F2r) signal transducer activity (F2r)
Anatomy Link Frequency
visceral 2
F2r (Mus musculus)
Pain Link Frequency Relevance Heat
Hyperalgesia 5 99.28 Very High Very High Very High
Visceral pain 5 98.76 Very High Very High Very High
qutenza 12 98.34 Very High Very High Very High
Antinociceptive 1 36.40 Quite Low
Pain 3 25.00 Low Low
Disease Link Frequency Relevance Heat
Hyperalgesia 5 99.28 Very High Very High Very High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super / Visceral Pain

5 98.76 Very High Very High Very High
Nociception 4 92.16 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Given the possible cross talk between PAR-2 and capsaicin receptors, we investigated if PAR-2 activation could facilitate capsaicin-evoked visceral pain and referred hyperalgesia in the mouse and also examined the effect of PAR-1 activation in this model.
Spec (examined) Regulation (effect) of Spec (examined) Positive_regulation (activation) of PAR-1 in visceral associated with hyperalgesia, visceral pain and qutenza
1) Confidence 0.18 Published 2004 Journal J. Pharmacol. Sci. Section Abstract Doc Link 15037813 Disease Relevance 0.64 Pain Relevance 1.24

General Comments

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