INT11761

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.42
First Reported 1992
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 13
Total Number 14
Disease Relevance 7.66
Pain Relevance 3.65

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nuclear envelope (DST) endoplasmic reticulum (DST) cytoplasm (DST)
cell adhesion (DST) cell motility (DST) nucleus (DST)
Anatomy Link Frequency
plaque 2
DST (Homo sapiens)
Pain Link Frequency Relevance Heat
Cholecystokinin 192 100.00 Very High Very High Very High
medulla 56 100.00 Very High Very High Very High
cINOD 6 99.84 Very High Very High Very High
depression 15 99.80 Very High Very High Very High
Pain 19 99.46 Very High Very High Very High
Inflammation 40 98.40 Very High Very High Very High
Spinal cord 19 97.96 Very High Very High Very High
backache 1 97.00 Very High Very High Very High
aspirin 1 96.96 Very High Very High Very High
Neuritis 2 96.08 Very High Very High Very High
Disease Link Frequency Relevance Heat
Depression 19 99.80 Very High Very High Very High
Alkalosis 1 99.80 Very High Very High Very High
Coronary Artery Disease 34 99.50 Very High Very High Very High
Pain 24 99.46 Very High Very High Very High
INFLAMMATION 41 98.40 Very High Very High Very High
Diabetes Mellitus 51 98.06 Very High Very High Very High
Hypoglycemia 21 97.48 Very High Very High Very High
Low Back Pain 1 97.00 Very High Very High Very High
Schizophrenia 166 96.92 Very High Very High Very High
Suicidal Behaviour 9 96.24 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Pain group, the specificity of DST non-suppression for depression was 82% and for sensitivity 24%.
Negative_regulation (suppression) of DST associated with pain and depression
1) Confidence 0.42 Published 1992 Journal Pain Section Abstract Doc Link 1594256 Disease Relevance 1.61 Pain Relevance 1.49
Coconut kernal, thus reduced the mutagenic and carcinogenic effect of chilli and DMH respectively.
Negative_regulation (reduced) of DMH
2) Confidence 0.35 Published 1997 Journal Indian J. Exp. Biol. Section Abstract Doc Link 9475077 Disease Relevance 0.14 Pain Relevance 0
Power to detect this effect size was reduced to 74% in the 2005/06 sample after allowing for the reduction in variation in BPA exposure levels.


Negative_regulation (reduction) of BPA
3) Confidence 0.35 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2800195 Disease Relevance 0 Pain Relevance 0
However, associations with diabetes seen in the 2003/04 NHANES survey was not evident in the current study, possibly because of the reduction in statistical power due to the lower levels of BPA in 2005/06, resulting in wide confidence intervals around estimates.
Spec (possibly) Negative_regulation (reduction) of BPA associated with diabetes mellitus
4) Confidence 0.34 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2800195 Disease Relevance 0.82 Pain Relevance 0.12
Our finding suggests that DMH inactivation may play a specific role in decreasing the HPA axis response after repeated bouts of IIH.
Negative_regulation (inactivation) of DMH associated with hypoglycemia
5) Confidence 0.33 Published 2004 Journal Am. J. Physiol. Regul. Integr. Comp. Physiol. Section Abstract Doc Link 14660476 Disease Relevance 0.51 Pain Relevance 0.08
The epinephrine, norepinephrine, and glucagon responses were not altered by DMH inactivation.
Negative_regulation (inactivation) of DMH
6) Confidence 0.29 Published 2004 Journal Am. J. Physiol. Regul. Integr. Comp. Physiol. Section Abstract Doc Link 14660476 Disease Relevance 0.42 Pain Relevance 0.08
Inactivation of the DMH selectively inhibits the ACTH and corticosterone responses to hypoglycemia.
Negative_regulation (Inactivation) of DMH associated with hypoglycemia
7) Confidence 0.29 Published 2004 Journal Am. J. Physiol. Regul. Integr. Comp. Physiol. Section Title Doc Link 14660476 Disease Relevance 0.50 Pain Relevance 0.07
Several studies in depressed patients have found an association of DST non-suppression (Jokinen and Nordstrom, 2009a; Jokinen et al., 2007; Mann et al., 2006) and suppression with suicide or suicide attempt (Black et al., 2002).
Negative_regulation (suppression) of DST associated with suicidal behaviour
8) Confidence 0.19 Published 2010 Journal Journal of Psychopharmacology (Oxford, England) Section Body Doc Link PMC2951595 Disease Relevance 1.35 Pain Relevance 0
Similarly, the intracellular pH was changed, with more alkalosis noted in DMH, which was reversed by NSAIDs.
Negative_regulation (reversed) of DMH associated with alkalosis and cinod
9) Confidence 0.07 Published 2009 Journal Oncol. Res. Section Abstract Doc Link 20225762 Disease Relevance 0.55 Pain Relevance 0.54
An inflammatory process which involved all plaques present in each CHD patient while absent or limited to one plaque in normal controls.
Negative_regulation (limited) of plaque in plaque associated with coronary artery disease and inflammation
10) Confidence 0.04 Published 2004 Journal Cardiovasc Ultrasound Section Body Doc Link PMC539295 Disease Relevance 1.39 Pain Relevance 0.29
In particular, definition of plaque composition seems not enough reproducible to provide an alternative independent standard to quantitative histology [14].
Negative_regulation (definition) of plaque in plaque
11) Confidence 0.04 Published 2004 Journal Cardiovasc Ultrasound Section Body Doc Link PMC539295 Disease Relevance 0.27 Pain Relevance 0.08
This pathway could contribute to the additive effect of CCK and CART peptide in the DMH.
Negative_regulation (effect) of DMH associated with cholecystokinin
12) Confidence 0.02 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2587474 Disease Relevance 0 Pain Relevance 0.76
An identical set of mice was used for determination of Fos immunoreactivity in NTS, PVN, and DMH.
Negative_regulation (determination) of DMH associated with medulla
13) Confidence 0.02 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2587474 Disease Relevance 0 Pain Relevance 0.10
CATX activity was measured in 25 mM CH3COONa/1 mM EDTA/5 mM DTT (pH 3.5) with 10 ?
Negative_regulation (measured) of CATX
14) Confidence 0.02 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2527007 Disease Relevance 0 Pain Relevance 0.05

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox