INT117683

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Context Info
Confidence 0.50
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.31
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (GSTM1) small molecule metabolic process (GSTM1) cytoplasm (GSTM1)
Anatomy Link Frequency
neurons 2
primary sensory neurons 2
GSTM1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 6 99.74 Very High Very High Very High
mu opioid receptor 1 95.76 Very High Very High Very High
Antihyperalgesic 5 91.12 High High
magnetoencephalography 6 84.72 Quite High
Electroencephalography 17 83.40 Quite High
MU agonist 3 75.00 Quite High
Hyperalgesia 1 54.56 Quite High
Pain 4 39.20 Quite Low
tail-flick 1 26.64 Quite Low
Acute pain 1 25.04 Quite Low
Disease Link Frequency Relevance Heat
Sprains And Strains 40 99.98 Very High Very High Very High
INFLAMMATION 5 99.74 Very High Very High Very High
Nicotine Addiction 4 93.48 High High
Severe Combined Immunodeficiency 6 81.92 Quite High
Hyperalgesia 1 54.56 Quite High
Pain 5 39.20 Quite Low
Ataxia 1 25.00 Low Low
Multiple Chemical Sensitivity 20 5.00 Very Low Very Low Very Low
Disease 11 5.00 Very Low Very Low Very Low
Hypersensitivity 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Table 3 shows the distribution of NAT2, GSTM1, GSTT1, and GSTP1 genotypes by self-reported chemical-related sensitivity score (?
Positive_regulation (shows) of Gene_expression (distribution) of GSTM1
1) Confidence 0.50 Published 2007 Journal Environ Health Section Body Doc Link PMC1802749 Disease Relevance 0.18 Pain Relevance 0
Peripheral inflammation leads to an increase in mu receptor present on the peripheral terminals of primary sensory neurons.
Positive_regulation (increase) of Gene_expression (present) of mu in primary sensory neurons associated with inflammation
2) Confidence 0.10 Published 2004 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 15054116 Disease Relevance 0.21 Pain Relevance 0.41
The mu rhythm results from the spontaneous firing of the sensorimotor neurons in synchrony around the ?
Positive_regulation (results) of Gene_expression (rhythm) of mu in neurons
3) Confidence 0.07 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2361218 Disease Relevance 0 Pain Relevance 0.17
Inter-strain variation in GTM profiles
Positive_regulation (variation) of Gene_expression (profiles) of GTM associated with sprains and strains
4) Confidence 0.07 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2798964 Disease Relevance 0.92 Pain Relevance 0

General Comments

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