INT117760

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Context Info
Confidence 0.42
First Reported 2004
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.36
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Cyp11a1)
Anatomy Link Frequency
cleavage 2
Cyp11a1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Opioid 1 94.68 High High
Pain 1 90.92 High High
adenocard 2 77.48 Quite High
Disease Link Frequency Relevance Heat
Apoptosis 1 91.28 High High
Pain 1 90.92 High High
Pulmonary Disease 1 90.68 High High
Muscular Spasm 1 89.96 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Effects of S-petasin on cyclic AMP production and enzyme activity of P450scc in rat zona fasciculata-reticularis cells.
Regulation (Effects) of Gene_expression (production) of P450scc
1) Confidence 0.42 Published 2004 Journal Eur. J. Pharmacol. Section Title Doc Link 15063152 Disease Relevance 0.27 Pain Relevance 0.16
Quantitative PCR analysis demonstrated dose- and androgen-specific modulation of mRNA expression for genes involved in steroidogenesis (StAR (steroidogenic acute regulatory) protein, P450scc (P450-mediated cholesterol side-chain cleavage), 20beta-HSD (20beta-hydroxysteroid dehydrogenase)) and cell growth control, namely--opioid growth factor receptor (OGF-R), progesterone receptor protein p23 (PR23P) and apoptosis-inducing TAF9-like domain 1 (TAF9).
Regulation (modulation) of Gene_expression (expression) of P450scc in cleavage associated with apoptosis and opioid
2) Confidence 0.10 Published 2009 Journal Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. Section Abstract Doc Link 19036348 Disease Relevance 0.09 Pain Relevance 0.09

General Comments

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