INT117796

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Context Info
Confidence 0.48
First Reported 2004
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 2.79
Pain Relevance 0.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (CPM) nucleolus (CPM) plasma membrane (CPM)
nucleus (CPM) cytoplasm (CPM)
Anatomy Link Frequency
plasma 2
face 1
B12 1
CPM (Homo sapiens)
Pain Link Frequency Relevance Heat
medulla 1 96.40 Very High Very High Very High
Spinal cord 1 91.36 High High
midbrain 1 89.44 High High
headache 10 88.60 High High
Enkephalin 1 80.88 Quite High
Dysuria 1 75.00 Quite High
Central nervous system 42 74.36 Quite High
intrathecal 2 45.08 Quite Low
Potency 6 5.00 Very Low Very Low Very Low
chemokine 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Acquired Immune Deficiency Syndrome Or Hiv Infection 256 99.48 Very High Very High Very High
Leukocytosis 56 98.48 Very High Very High Very High
Anaemia 1 94.76 High High
Viral Meningitis 12 92.40 High High
Infection 256 89.44 High High
Photophobia 2 89.12 High High
Headache 10 88.60 High High
Macrocytic Anemia 2 86.92 High High
Meningitis 6 81.84 Quite High
Abnormal Reflex 1 81.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Through this GPI anchor, and presumably via some positively charged side-chains of the C-terminal domain, the CPM molecule may interact with the membrane in such a way that its active centre will face alongside, i.e. well suited to interact with other membrane-bound protein substrates or small peptides.
CPM molecule Binding (interact) of in face
1) Confidence 0.48 Published 2004 Journal J. Mol. Biol. Section Abstract Doc Link 15066430 Disease Relevance 0 Pain Relevance 0.08
We assume that B12 deficiency was involved in the formation of CPM/EPM and the neurological symptoms in our patient.
CPM Binding (formation) of in B12
2) Confidence 0.47 Published 2007 Journal Rinsho Shinkeigaku Section Abstract Doc Link 17511290 Disease Relevance 0.75 Pain Relevance 0.21
Thus, a first manner to implement CPM would be:

(23)r(SM(?

CPM Binding (implement) of
3) Confidence 0.12 Published 2007 Journal Frontiers in Neurorobotics Section Body Doc Link PMC2533589 Disease Relevance 0 Pain Relevance 0
L, and was associated with plasma VLs near or above 10,000 cpm.
cpm Binding (associated) of in plasma
4) Confidence 0.03 Published 2005 Journal BMC Infect Dis Section Body Doc Link PMC1299327 Disease Relevance 1.72 Pain Relevance 0.15
His CSF VL was high (19,700 cpm), his plasma HIV level was nearly tenfold lower (2,800 cpm), and the usual ?
cpm Binding (lower) of in plasma associated with acquired immune deficiency syndrome or hiv infection
5) Confidence 0.03 Published 2005 Journal BMC Infect Dis Section Body Doc Link PMC1299327 Disease Relevance 0.32 Pain Relevance 0

General Comments

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