INT117830

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Context Info
Confidence 0.28
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.41
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (CPOX) small molecule metabolic process (CPOX) oxidoreductase activity (CPOX)
cytoplasm (CPOX)
Anatomy Link Frequency
PGE2 2
CPOX (Homo sapiens)
Pain Link Frequency Relevance Heat
Analgesic 1 92.36 High High
Inflammation 1 84.40 Quite High
Pain 1 83.72 Quite High
Inflammatory mediators 1 75.00 Quite High
cytokine 1 46.80 Quite Low
Disease Link Frequency Relevance Heat
INFLAMMATION 2 84.40 Quite High
Pain 1 83.72 Quite High
Cancer 1 81.60 Quite High
Necrosis 1 81.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The IC50-values obtained for the inhibition of lipopolysaccharide (LPS)-induced release of prostaglandin E2 (PGE2) reflecting cyclooxygenase (COX)-2-mediated PGE2 release were 47 microg/ml and 0.6 microg/ml, for the Salix extract 1520L and rofecoxib-like research compound L745337, respectively.
Positive_regulation (induced) of Localization (release) of COX in PGE2
1) Confidence 0.28 Published 2004 Journal Phytomedicine Section Abstract Doc Link 15070163 Disease Relevance 0.41 Pain Relevance 0.26

General Comments

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