INT11788

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.46
First Reported 1986
Last Reported 2010
Negated 2
Speculated 1
Reported most in Abstract
Documents 36
Total Number 38
Disease Relevance 10.08
Pain Relevance 9.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
respiratory 4
respiratory system 2
upper 2
muscle 1
Rrsv (Mus musculus)
Pain Link Frequency Relevance Heat
addiction 6 100.00 Very High Very High Very High
qutenza 65 99.76 Very High Very High Very High
opiate 20 99.72 Very High Very High Very High
anesthesia 31 99.58 Very High Very High Very High
lidocaine 8 98.76 Very High Very High Very High
antagonist 1 98.68 Very High Very High Very High
bradykinin 6 98.62 Very High Very High Very High
Opioid 2 98.48 Very High Very High Very High
Morphine 8 97.32 Very High Very High Very High
Codeine 12 96.48 Very High Very High Very High
Disease Link Frequency Relevance Heat
Cough 46 99.98 Very High Very High Very High
Occupational Lung Diseases 4 99.84 Very High Very High Very High
Sprains And Strains 89 99.42 Very High Very High Very High
Respiratory Syncytial Virus 143 98.80 Very High Very High Very High
Asthma 43 98.54 Very High Very High Very High
Coronary Heart Disease 28 98.44 Very High Very High Very High
Borrelia Infection 98 98.36 Very High Very High Very High
Increased Venous Pressure Under Development 19 94.16 High High
Rhinitis 2 91.76 High High
INFLAMMATION 19 90.96 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Airway responses were measured in terms of PD(100) (dose of Mch causing 100% increase from baseline Rrs) and Rrs,max (% increase from baseline at the maximal plateau response) and expressed as % control (mean +/- SE).
Positive_regulation (increase) of Rrs
1) Confidence 0.46 Published 2000 Journal Pediatr. Res. Section Abstract Doc Link 11102546 Disease Relevance 0.49 Pain Relevance 0.14
However, the flow dependence of RL and Rrs indicates that their measured values will be affected by all factors that modify expiratory flow, e.g., respiratory system elastance, equipment resistance, and the presence of respiratory muscle activity.
Positive_regulation (dependence) of Rrs in muscle associated with addiction
2) Confidence 0.46 Published 1989 Journal J. Appl. Physiol. Section Abstract Doc Link 2793695 Disease Relevance 0.06 Pain Relevance 0.18
Airway responses were measured in terms of PD(100) (dose of Mch causing 100% increase from baseline Rrs) and Rrs,max (% increase from baseline at the maximal plateau response) and expressed as % control (mean +/- SE).
Positive_regulation (increase) of Rrs
3) Confidence 0.40 Published 2000 Journal Pediatr. Res. Section Abstract Doc Link 11102546 Disease Relevance 0.49 Pain Relevance 0.14
A/J mice had a higher baseline Rrs, yet the response to ACh was independent of baseline Rrs.
Neg (independent) Positive_regulation (independent) of Rrs
4) Confidence 0.40 Published 1995 Journal J. Appl. Physiol. Section Abstract Doc Link 7592218 Disease Relevance 0 Pain Relevance 0
ACh induced a dose-dependent rise in Rrs and Ers in A/J mice, whereas minimal changes were observed in C3H/HeJ mice.
Positive_regulation (induced) of Rrs
5) Confidence 0.40 Published 1995 Journal J. Appl. Physiol. Section Abstract Doc Link 7592218 Disease Relevance 0 Pain Relevance 0
Rrs increased on average by 81% after lidocaine spray and by 68% after lidocaine paste (p < 0.005, respectively) with no difference in the magnitude of Rrs increase between the two modes of anaesthesia studied.
Positive_regulation (increased) of Rrs
6) Confidence 0.40 Published 1995 Journal Intensive Care Med Section Body Doc Link 8636524 Disease Relevance 0 Pain Relevance 0
Rrs increased on average by 81% after lidocaine spray and by 68% after lidocaine paste (p < 0.005, respectively) with no difference in the magnitude of Rrs increase between the two modes of anaesthesia studied.
Positive_regulation (increase) of Rrs
7) Confidence 0.40 Published 1995 Journal Intensive Care Med Section Body Doc Link 8636524 Disease Relevance 0 Pain Relevance 0
Laryngeal dysfunction may be one mechanisms involved in Rrs increase following upper airway topical anaesthesia.
Positive_regulation (increase) of Rrs in upper
8) Confidence 0.40 Published 1995 Journal Intensive Care Med Section Body Doc Link 8636524 Disease Relevance 0 Pain Relevance 0
CONCLUSIONS: Topical upper airway anaesthesia transiently increases Rrs with no specific effects regarding the drug presentation.
Positive_regulation (increases) of Rrs in upper
9) Confidence 0.40 Published 1995 Journal Intensive Care Med Section Body Doc Link 8636524 Disease Relevance 0 Pain Relevance 0
The inhibitory effect of 3-isobutyryl-2-isopropylpyrazolo[1,5-alpha]pyridine (KC-404) on aerosolized methacholine- and histamine-induced increase in total respiratory resistance (Rrs) was determined in monkeys using the forced 3 Hz oscillation method and was compared with the effect of aminophylline.
Positive_regulation (increase) of Rrs in respiratory
10) Confidence 0.19 Published 1986 Journal Arch Int Pharmacodyn Ther Section Abstract Doc Link 3800509 Disease Relevance 0.07 Pain Relevance 0
KC-404 also inhibited the histamine-induced increase in Rrs.
Positive_regulation (increase) of Rrs
11) Confidence 0.19 Published 1986 Journal Arch Int Pharmacodyn Ther Section Abstract Doc Link 3800509 Disease Relevance 0.16 Pain Relevance 0
All of the i.v. administered pyrazolopyridine derivatives showed an inhibition of the increase in Rrs induced by aerosolized methacholine.
Positive_regulation (induced) of Rrs
12) Confidence 0.19 Published 1986 Journal Arch Int Pharmacodyn Ther Section Abstract Doc Link 3800509 Disease Relevance 0.15 Pain Relevance 0
We concluded that in children with mild to moderate asthma, endotracheal intubation during sevoflurane anesthesia was associated with increase in Rrs that was not seen in nonasthmatic children.
Positive_regulation (increase) of Rrs associated with asthma and anesthesia
13) Confidence 0.19 Published 1999 Journal Anesth. Analg. Section Abstract Doc Link 10553830 Disease Relevance 0.42 Pain Relevance 0.28
Intubation was associated with a significant increase in Rrs in asthmatics (17% +/- 49%), whereas in normal children, Rrs slightly decreased (-4% +/- 39%).
Positive_regulation (increase) of Rrs associated with occupational lung diseases
14) Confidence 0.19 Published 1999 Journal Anesth. Analg. Section Abstract Doc Link 10553830 Disease Relevance 0.47 Pain Relevance 0.28
Asthmatic children having their tracheas intubated with sevoflurane often have an increase in respiratory system resistance (Rrs).
Positive_regulation (increase) of Rrs in respiratory system associated with asthma
15) Confidence 0.19 Published 2001 Journal Anesth. Analg. Section Abstract Doc Link 11574353 Disease Relevance 0.25 Pain Relevance 0.20
We conclude that when using sevoflurane in mildly to moderately asthmatic children, a preanesthetic treatment with inhaled salbutamol is protective of an increase in Rrs.
Positive_regulation (increase) of Rrs associated with asthma
16) Confidence 0.19 Published 2001 Journal Anesth. Analg. Section Abstract Doc Link 11574353 Disease Relevance 0.67 Pain Relevance 0.20
After the muscarinic receptor antagonist ipratropium bromide (120 micrograms) was inhaled, leukotriene D4 increased Rrs by 103 +/- 9% (P less than 0.001).
Positive_regulation (increased) of Rrs associated with antagonist
17) Confidence 0.19 Published 1989 Journal J. Appl. Physiol. Section Abstract Doc Link 2529237 Disease Relevance 0.16 Pain Relevance 0.46
Mean Rrs was elevated with a negative frequency dependence, and mean Xrs was decreased.
Positive_regulation (elevated) of Rrs associated with addiction
18) Confidence 0.19 Published 1991 Journal Eur. Respir. J. Section Abstract Doc Link 1783085 Disease Relevance 0.31 Pain Relevance 0.36
It is concluded that the increased in Rrs,min and RL,min could be explained by opioid bronchoconstriction.
Positive_regulation (increased) of Rrs associated with opioid
19) Confidence 0.19 Published 1992 Journal Can J Anaesth Section Abstract Doc Link 1596970 Disease Relevance 0 Pain Relevance 0.26
The Rrs,min and RL,min increased at two, five and ten minutes and the RL,max at five and ten minutes.
Positive_regulation (increased) of Rrs
20) Confidence 0.19 Published 1992 Journal Can J Anaesth Section Abstract Doc Link 1596970 Disease Relevance 0 Pain Relevance 0.25

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox