INT117911

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Context Info
Confidence 0.04
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.90
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (MAPK1, BIRC2) cytosol (MAPK1, BIRC2) nucleoplasm (MAPK1)
mitochondrion (MAPK1) Golgi apparatus (MAPK1) intracellular (BIRC2)
MAPK1 (Homo sapiens)
BIRC2 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 1 81.44 Quite High
cINOD 1 74.44 Quite High
Disease Link Frequency Relevance Heat
Stress 1 96.36 Very High Very High Very High
Apoptosis 5 84.00 Quite High
Colon Cancer 5 76.32 Quite High
INFLAMMATION 1 74.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Immunoblots and transcriptional reporter assays using specific inhibitors, as well as expression of constitutively active forms of MEK1 and MKK3, showed that c-IAP2 induction by cAMP is regulated predominantly through ERK1/2 and p38 MAPK and suggested involvement of p90 ribosomal protein S6 kinase and mitogen and stress response kinase-1 as well.
ERK1/2 Regulation (regulated) of Positive_regulation (induction) of c-IAP2 associated with stress
1) Confidence 0.04 Published 2004 Journal J. Biol. Chem. Section Abstract Doc Link 15078890 Disease Relevance 0.90 Pain Relevance 0.12

General Comments

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