INT117913

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Context Info
Confidence 0.15
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.81
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (BIRC2) cell differentiation (CREM) signal transduction (CREM)
intracellular (BIRC2) nucleus (CREM) DNA binding (CREM)
Anatomy Link Frequency
colon 2
CREM (Homo sapiens)
BIRC2 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 1 96.64 Very High Very High Very High
agonist 1 78.08 Quite High
Disease Link Frequency Relevance Heat
Apoptosis 5 100.00 Very High Very High Very High
Colon Cancer 5 99.78 Very High Very High Very High
INFLAMMATION 1 96.44 Very High Very High Very High
Stress 1 27.76 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We recently reported that cAMP suppresses apoptosis in colon cancer cells and induces cellular inhibitor of apoptosis protein-2 (c-IAP2) via a cAMP-responsive element (CRE), suggesting a mechanism for chemoprevention of colon cancer by non-steroidal anti-inflammatory drugs.
cAMP-responsive element Positive_regulation (induces) of Negative_regulation (inhibitor) of apoptosis protein-2 in colon associated with inflammation, colon cancer, cinod and apoptosis
1) Confidence 0.15 Published 2004 Journal J. Biol. Chem. Section Abstract Doc Link 15078890 Disease Relevance 0.81 Pain Relevance 0.14

General Comments

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