INT1180

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.77
First Reported 1975
Last Reported 2011
Negated 0
Speculated 3
Reported most in Abstract
Documents 63
Total Number 68
Disease Relevance 27.33
Pain Relevance 10.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Ren) extracellular space (Ren) extracellular region (Ren)
intracellular (Ren) response to stress (Ren)
Anatomy Link Frequency
plasma 28
renal cortex 6
myocytes 3
sympathetic nervous system 2
gonadotrophs 2
Ren (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Clonidine 17 99.98 Very High Very High Very High
Morphine 8 99.84 Very High Very High Very High
fibrosis 43 99.78 Very High Very High Very High
Catecholamine 4 99.68 Very High Very High Very High
anesthesia 47 99.52 Very High Very High Very High
Inflammation 126 99.36 Very High Very High Very High
fluoxetine 14 99.08 Very High Very High Very High
diclofenac 2 98.76 Very High Very High Very High
antagonist 166 98.44 Very High Very High Very High
imagery 12 98.08 Very High Very High Very High
Disease Link Frequency Relevance Heat
Hypertension 435 100.00 Very High Very High Very High
Cv Unclassified Under Development 18 100.00 Very High Very High Very High
Disorders Of Creatine Metabolism 3 100.00 Very High Very High Very High
Sepsis 154 99.92 Very High Very High Very High
Fibrosis 38 99.78 Very High Very High Very High
Acid Base Imbalance 1 99.78 Very High Very High Very High
Coronary Heart Disease 39 99.76 Very High Very High Very High
Hypotension 39 99.66 Very High Very High Very High
Pressure And Volume Under Development 36 99.66 Very High Very High Very High
Pressure Volume 2 Under Development 18 99.62 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In conclusion, no evidence was found for myocardial renin synthesis in the normal adult rat heart, and myocardial renin decays to near zero levels after 48-hour BNX.
Gene_expression (synthesis) of renin in heart
1) Confidence 0.77 Published 2001 Journal Basic Res. Cardiol. Section Abstract Doc Link 11770086 Disease Relevance 0 Pain Relevance 0
The source of myocardial renin maybe direct cardiac renin gene expression, or plasma renin of renal origin.
Gene_expression (expression) of renin in plasma
2) Confidence 0.77 Published 2001 Journal Basic Res. Cardiol. Section Abstract Doc Link 11770086 Disease Relevance 0.10 Pain Relevance 0
The morphological characteristics of the hamartomatous abnormality are described and evidences are put forward which would suggest that the liver lesion might have been the site of the abnormal renin production which was responsible for the systemic arterial hypertension.
Gene_expression (production) of renin in liver associated with pressure and volume under development
3) Confidence 0.76 Published 1975 Journal Virchows Arch A Pathol Anat Histol Section Abstract Doc Link 804756 Disease Relevance 0.60 Pain Relevance 0.09
The intracerebral administration of renin and angiotensin II produces an increase in latencies to thermoalgesic stimuli; this is reduced, as is immobilization stress, by naloxone and saralasin.
Gene_expression (produces) of renin associated with stress and narcan
4) Confidence 0.73 Published 1986 Journal Pain Section Abstract Doc Link 3540814 Disease Relevance 0.43 Pain Relevance 0.58
It is suggested that this increase is hardly due to an interception of the feedback, but to the concomitant fall in blood pressure, as a similar hypotension and increase in plasma renin is produced by dihydralazine.
Gene_expression (produced) of plasma renin in plasma associated with hypotension
5) Confidence 0.68 Published 1975 Journal Acta Pathol Microbiol Scand A Section Abstract Doc Link 170788 Disease Relevance 0.51 Pain Relevance 0
Renin-depletion, described as a decrease in renal cortex and plasma renin levels, was produced by clipping one renal artery of a rat and leaving the contralateral kidney in place (two kidney one clip hypertension), One month later the clipped kidney was removed and after 24 h recovery such rats were found to be renin depleted: renal cortex and plasma renin levels were 8 and 63% of normal respectively. 2.
Gene_expression (levels) of Renin in plasma associated with hypertension
6) Confidence 0.68 Published 1981 Journal Pflugers Arch. Section Abstract Doc Link 7033921 Disease Relevance 0.37 Pain Relevance 0.12
Renin-depletion, described as a decrease in renal cortex and plasma renin levels, was produced by clipping one renal artery of a rat and leaving the contralateral kidney in place (two kidney one clip hypertension), One month later the clipped kidney was removed and after 24 h recovery such rats were found to be renin depleted: renal cortex and plasma renin levels were 8 and 63% of normal respectively. 2.
Gene_expression (levels) of renin in plasma associated with hypertension
7) Confidence 0.68 Published 1981 Journal Pflugers Arch. Section Abstract Doc Link 7033921 Disease Relevance 0.37 Pain Relevance 0.12
Renin-depletion, described as a decrease in renal cortex and plasma renin levels, was produced by clipping one renal artery of a rat and leaving the contralateral kidney in place (two kidney one clip hypertension), One month later the clipped kidney was removed and after 24 h recovery such rats were found to be renin depleted: renal cortex and plasma renin levels were 8 and 63% of normal respectively. 2.
Gene_expression (produced) of Renin in plasma associated with hypertension
8) Confidence 0.68 Published 1981 Journal Pflugers Arch. Section Abstract Doc Link 7033921 Disease Relevance 0.37 Pain Relevance 0.13
The source of myocardial renin maybe direct cardiac renin gene expression, or plasma renin of renal origin.
Gene_expression (source) of plasma renin in plasma
9) Confidence 0.68 Published 2001 Journal Basic Res. Cardiol. Section Abstract Doc Link 11770086 Disease Relevance 0.10 Pain Relevance 0
Acid dialysis (pH 3.3) of normal plasma resulted in a significant increase in renin concentration, confirming the presence of an inactive renin (prorenin) in this species.
Gene_expression (presence) of renin in plasma
10) Confidence 0.68 Published 1981 Journal Endocrinology Section Abstract Doc Link 7007027 Disease Relevance 0.08 Pain Relevance 0.21
[Renin activity and functional status of the adrenal cortex in surgical intervention during ketamine anesthesia].
Gene_expression (activity) of Renin in adrenal cortex associated with anesthesia and ketamine
11) Confidence 0.67 Published 1979 Journal Vestn. Khir. Im. I. I. Grek. Section Title Doc Link 442425 Disease Relevance 0.09 Pain Relevance 0.40
Propranolol partially blocked the increase in plasma renin concentration produced by anesthetics.
Gene_expression (produced) of plasma renin in plasma
12) Confidence 0.67 Published 1985 Journal Eur. J. Pharmacol. Section Abstract Doc Link 3894036 Disease Relevance 0.27 Pain Relevance 0.17
Renal renin activity in the clipped kidney was higher than in the nonclipped kidney in groups 1 and 2.
Gene_expression (activity) of renin in kidney
13) Confidence 0.66 Published 1988 Journal Am. J. Physiol. Section Abstract Doc Link 3059819 Disease Relevance 0.14 Pain Relevance 0.39
[Relation between plasma renin level and antihypertensive response to nicardipine].
Gene_expression (level) of renin in plasma
14) Confidence 0.62 Published 1995 Journal Arch Mal Coeur Vaiss Section Title Doc Link 8745614 Disease Relevance 0.27 Pain Relevance 0.05
It did not affect baseline plasma adrenocorticotropic hormone levels and renin activity, but decreased plasma corticosterone levels.
Gene_expression (levels) of renin in plasma
15) Confidence 0.61 Published 1999 Journal Neuroscience Section Abstract Doc Link 10392854 Disease Relevance 0.58 Pain Relevance 0.46
Renin-depletion, described as a decrease in renal cortex and plasma renin levels, was produced by clipping one renal artery of a rat and leaving the contralateral kidney in place (two kidney one clip hypertension), One month later the clipped kidney was removed and after 24 h recovery such rats were found to be renin depleted: renal cortex and plasma renin levels were 8 and 63% of normal respectively. 2.
Gene_expression (levels) of renin in plasma associated with hypertension
16) Confidence 0.60 Published 1981 Journal Pflugers Arch. Section Abstract Doc Link 7033921 Disease Relevance 0.42 Pain Relevance 0.16
On the other hand, the increase in secretion of renin produced by inactin anesthesia does not appear to be mediated by the sympathetic nervous system.
Gene_expression (produced) of renin in sympathetic nervous system associated with anesthesia
17) Confidence 0.60 Published 1988 Journal Neuropharmacology Section Abstract Doc Link 3072488 Disease Relevance 0 Pain Relevance 0.24
Pharmacological evidence that the sympathetic nervous system mediates the increase in renin secretion produced by immobilization and head-up tilt in rats.
Gene_expression (produced) of renin in head
18) Confidence 0.60 Published 1988 Journal Neuropharmacology Section Title Doc Link 3072488 Disease Relevance 0 Pain Relevance 0.22
The source of myocardial renin maybe direct cardiac renin gene expression, or plasma renin of renal origin.
Gene_expression (expression) of renin in plasma
19) Confidence 0.60 Published 2001 Journal Basic Res. Cardiol. Section Abstract Doc Link 11770086 Disease Relevance 0.10 Pain Relevance 0
Furthermore, we investigated the organ-related sources of plasma inactive renin which markedly increased after total nephrectomy.
Gene_expression (sources) of renin in plasma
20) Confidence 0.60 Published 1987 Journal Nippon Naibunpi Gakkai Zasshi Section Abstract Doc Link 3322883 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox