INT118046

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Context Info
Confidence 0.34
First Reported 2004
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.14
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (RAN) GTPase activity (RAN) cytoplasm (RAN)
cytosol (RAN) signal transduction (RAN) mitosis (RAN)
RAN (Homo sapiens)
Pain Link Frequency Relevance Heat
Opioid 2 99.46 Very High Very High Very High
Enkephalin 1 96.96 Very High Very High Very High
local anesthetic 5 50.00 Quite Low
Disease Link Frequency Relevance Heat
Skin Cancer 2 69.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Regulation of cell proliferation by the opioid growth factor receptor is dependent on karyopherin beta and Ran for nucleocytoplasmic trafficking.
Regulation (dependent) of Ran associated with opioid
1) Confidence 0.34 Published 2010 Journal Exp. Biol. Med. (Maywood) Section Title Doc Link 20705629 Disease Relevance 0.14 Pain Relevance 0.29
Critically requiring G alpha q-protein function, this effect is located downstream of guanosine diphosphate-guanosine triphosphate exchange and is not dependent on increased guanosine triphosphatase activity, phosphatases, or protein kinases.


Neg (not) Regulation (dependent) of guanosine triphosphatase
2) Confidence 0.07 Published 2004 Journal Anesthesiology Section Body Doc Link 15087620 Disease Relevance 0 Pain Relevance 0

General Comments

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