INT118082

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Context Info
Confidence 0.00
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.50
Pain Relevance 0.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (APP, Casp3) cytosol (APP, Casp3) mitochondrion (Casp3)
Golgi apparatus (APP) intracellular (Casp3) extracellular matrix organization (APP)
Anatomy Link Frequency
neuronal 1
APP (Homo sapiens)
Casp3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Abeta 12 100.00 Very High Very High Very High
Morphine 1 98.90 Very High Very High Very High
Eae 1 90.04 High High
Disease Link Frequency Relevance Heat
Neurodegenerative Disease 1 99.36 Very High Very High Very High
Drug Induced Neurotoxicity 4 75.16 Quite High
Alzheimer's Dementia 2 75.00 Quite High
Toxicity 1 75.00 Quite High
Apoptosis 2 58.84 Quite High
Death 1 47.60 Quite Low
Disease 1 44.68 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Morphine, which activates CaMKII via micro receptors, augments Abeta-induced LDH release, caspase-2 and caspase-3 activities and neuronal apoptosis.
Abeta Positive_regulation (induced) of caspase-3 in neuronal associated with neurodegenerative disease, abeta and morphine
1) Confidence 0.00 Published 2004 Journal Eur. J. Neurosci. Section Abstract Doc Link 15090032 Disease Relevance 0.50 Pain Relevance 0.54

General Comments

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