INT11814

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Context Info
Confidence 0.63
First Reported 1985
Last Reported 2010
Negated 2
Speculated 0
Reported most in Body
Documents 43
Total Number 43
Disease Relevance 31.71
Pain Relevance 6.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Alb) enzyme binding (Alb) DNA binding (Alb)
protein complex (Alb) response to stress (Alb) cytoplasm (Alb)
Anatomy Link Frequency
brain 3
blood 3
urine 3
plasma 2
cerebrospinal fluid 2
Alb (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 27 100.00 Very High Very High Very High
antagonist 46 99.98 Very High Very High Very High
Pain 18 99.88 Very High Very High Very High
Morphine 21 99.32 Very High Very High Very High
imagery 56 99.28 Very High Very High Very High
Arthritis 54 97.72 Very High Very High Very High
substance P 4 97.52 Very High Very High Very High
Paracetamol 11 96.84 Very High Very High Very High
agonist 68 96.70 Very High Very High Very High
Spinal cord 80 96.08 Very High Very High Very High
Disease Link Frequency Relevance Heat
Disease 586 100.00 Very High Very High Very High
Disorders Of Creatine Metabolism 7 100.00 Very High Very High Very High
Hyperuricemia 1 99.96 Very High Very High Very High
Pain 17 99.88 Very High Very High Very High
Aspergillus Infection 88 99.70 Very High Very High Very High
Aids-related Complex 441 99.68 Very High Very High Very High
Sprains And Strains 267 99.68 Very High Very High Very High
Pressure And Volume Under Development 84 99.28 Very High Very High Very High
Muscle Disease 1 99.24 Very High Very High Very High
Toxicity 54 99.14 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Albumin, which is a major secretory protein of the liver, is induced in fetal liver and its expression is maintained in the adult liver [27].
Positive_regulation (induced) of Albumin in liver
1) Confidence 0.63 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2185514 Disease Relevance 0.33 Pain Relevance 0
Repopulation of the h-hepatocytes in the liver increased the blood Alb concentration and decreased the ALT level, indicating that h-hepatocytes contributed to the improvement of m-liver function [8].
Positive_regulation (increased) of Alb in blood
2) Confidence 0.47 Published 2009 Journal PPAR Research Section Body Doc Link PMC2768028 Disease Relevance 0.17 Pain Relevance 0
Blood flow was assessed by laser Doppler flowmetry and plasma extravasation by 125I-albumin accumulation.
Positive_regulation (accumulation) of albumin in plasma
3) Confidence 0.45 Published 2005 Journal Eur. J. Pharmacol. Section Abstract Doc Link 15659318 Disease Relevance 0.86 Pain Relevance 0.31
At 3 months, a significant increase in serum albumin level was observed in patients administered nocturnal BCAAs, but not daytime BCAAs.
Positive_regulation (increase) of serum albumin
4) Confidence 0.44 Published 2010 Journal Journal of Nutrition and Metabolism Section Body Doc Link PMC3017957 Disease Relevance 0.77 Pain Relevance 0
Morphine treatment was associated with an increase in serum albumin, SGPT, BUN, and alkaline phosphatase indicative of hepatic damage.
Positive_regulation (increase) of albumin associated with morphine
5) Confidence 0.37 Published 1994 Journal Fundam Appl Toxicol Section Abstract Doc Link 8056200 Disease Relevance 0 Pain Relevance 0.96
Interestingly, there was no difference in the increase in serum SEAP between males and females at day 1, that is, an approximate 13-fold elevation in both groups (Figure 2C, inset).
Positive_regulation (increase) of serum SEAP
6) Confidence 0.33 Published 2008 Journal Environ Health Perspect Section Body Doc Link PMC2265056 Disease Relevance 0 Pain Relevance 0
However, although significant elevations of serum SEAP continued in females for at least 3 weeks, the degree of elevation was lower than that in males (Figure 2C).
Positive_regulation (elevations) of serum SEAP
7) Confidence 0.33 Published 2008 Journal Environ Health Perspect Section Body Doc Link PMC2265056 Disease Relevance 0.06 Pain Relevance 0
Their main symptom was severe muscle pain arising from rhabdomyolysis, which was usually accompanied by the discharge of black urine and abnormal elevation of serum creatine phosphokinase.
Positive_regulation (elevation) of serum creatine phosphokinase in urine associated with pain, disorders of creatine metabolism, rhabdomyolysis and myalgia
8) Confidence 0.32 Published 2009 Journal Shokuhin Eiseigaku Zasshi Section Abstract Doc Link 19897955 Disease Relevance 0.68 Pain Relevance 0.10
The repopulation after h-hepatocyte transplantation was easily monitored by the increase in the h-Alb concentration in the host blood, and the expansion of h-hepatocyte colonies was visualized by immunohistological staining of liver sections with h-specific anti-cytokeratin (CK) 8/18 antibodies.
Positive_regulation (increase) of h-Alb in blood
9) Confidence 0.32 Published 2009 Journal PPAR Research Section Body Doc Link PMC2768028 Disease Relevance 0.55 Pain Relevance 0
Oedema formation was concomitantly assessed by the extravascular accumulation of i.v. injected (125)I-albumin.
Positive_regulation (accumulation) of I-albumin associated with pressure and volume under development
10) Confidence 0.30 Published 2006 Journal Vascul. Pharmacol. Section Abstract Doc Link 16914387 Disease Relevance 0.70 Pain Relevance 0.26
Observation of the albumin - Evan’s blue dye complex also depicted tumor vasculature [Fig. 3(a)
Positive_regulation (Observation) of albumin in vasculature associated with cancer
11) Confidence 0.28 Published 2010 Journal Biomedical Optics Express Section Body Doc Link PMC3018094 Disease Relevance 0.33 Pain Relevance 0.07
Intradermally injected substance P (30-300 pmol), NK(1) agonists septide (3-30 pmol) and GR-73632 (3-30 pmol), and the mast cell-degranulating agent, compound 48/80 induced dose-dependent edema in wild-type skin, measured by the accumulation of intravenously injected (125)I-labeled albumin.
Positive_regulation (accumulation) of albumin in skin associated with pressure and volume under development, agonist and substance p
12) Confidence 0.28 Published 1999 Journal Am. J. Physiol. Section Abstract Doc Link 10444554 Disease Relevance 0.80 Pain Relevance 0.34
The lack of any lung damage associated with the PCN treatment was further supported by the absence of any increase in the levels of serum albumin (Figure 3C) and lactate dehydrogenase (Figure 3D) recovered in the BALF of these mice at this time and the absence of any weight loss during the PCN treatment regimen (data not shown).
Positive_regulation (increase) of serum albumin in lung associated with weight loss
13) Confidence 0.27 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2743193 Disease Relevance 0.48 Pain Relevance 0
In CBA/J x DBA/2 mice we observed a time course increase of albumin to creatinine ratio, reaching maximum values at day 15 of gestation.
Positive_regulation (increase) of albumin
14) Confidence 0.27 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2965104 Disease Relevance 0.99 Pain Relevance 0
In CBA/J x DBA/2 mice, a time-course increase in urine albumin to creatinine ratio (ACR), that reaches statistic significance at day 10 of pregnancy, was observed (Fig 1C).
Positive_regulation (increase) of albumin in urine
15) Confidence 0.27 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2965104 Disease Relevance 0.78 Pain Relevance 0.03
Administration of corn oil alone did not cause elevation of serum SEAP (data not shown).
Positive_regulation (elevation) of serum SEAP
16) Confidence 0.26 Published 2008 Journal Environ Health Perspect Section Body Doc Link PMC2265056 Disease Relevance 0.06 Pain Relevance 0.04
Significant decreases in serum albumin and A/G ratio were observed in EtOH alone-fed mice compared with those in normal animals, and their reductions were further induced in mice treated with AAP and EtOH.
Positive_regulation (decreases) of albumin
17) Confidence 0.24 Published 2002 Journal Int. Immunopharmacol. Section Abstract Doc Link 11789665 Disease Relevance 0.09 Pain Relevance 0.38
The A/J had significantly greater epithelial damage following MMA-SS exposure compared to the C57BL/6J strain as shown by the increased albumin in the BAL.
Positive_regulation (increased) of albumin in MMA associated with aids-related complex and sprains and strains
18) Confidence 0.23 Published 2008 Journal Part Fibre Toxicol Section Body Doc Link PMC2546436 Disease Relevance 2.12 Pain Relevance 0
Both strains in the S-Cr-exposed groups had increased albumin but no strain differences were noted.
Positive_regulation (increased) of albumin associated with sprains and strains
19) Confidence 0.23 Published 2008 Journal Part Fibre Toxicol Section Body Doc Link PMC2546436 Disease Relevance 1.88 Pain Relevance 0.03
In contrast, DRESSA25 mice placed in the room for 3 hr without exposure to polluted air showed no increases in the level of serum SEAP [Supplemental Material, Figure 2 (online at http://www.ehponline.org/members/2007/10722/suppl.pdf)].
Neg (no) Positive_regulation (increases) of serum SEAP
20) Confidence 0.22 Published 2008 Journal Environ Health Perspect Section Body Doc Link PMC2265056 Disease Relevance 0.07 Pain Relevance 0.03

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