INT118152

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Context Info
Confidence 0.09
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.60
Pain Relevance 1.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (Aox1) cytoplasm (Aox1)
Anatomy Link Frequency
sciatic nerve 1
Aox1 (Mus musculus)
Pain Link Frequency Relevance Heat
Sciatic nerve 9 100.00 Very High Very High Very High
Morphine 6 100.00 Very High Very High Very High
Spinal cord 4 92.96 High High
Neuropathic pain 4 92.52 High High
Thermal hyperalgesia 1 84.60 Quite High
Lasting pain 1 82.56 Quite High
alcohol 14 80.24 Quite High
Kinase C 7 75.00 Quite High
intrathecal 1 63.32 Quite High
neuralgia 3 25.00 Low Low
Disease Link Frequency Relevance Heat
Hypertrophy 4 96.36 Very High Very High Very High
Stress 7 95.08 Very High Very High Very High
Neuropathic Pain 4 92.52 High High
Apoptosis 41 91.44 High High
Hyperalgesia 1 84.60 Quite High
Syndrome 1 83.12 Quite High
Pain 1 82.56 Quite High
Natriuresis 1 66.36 Quite High
Coronary Heart Disease 9 62.56 Quite High
Targeted Disruption 4 61.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As the major metabolite of ethanol, acetaldehyde enhances free radical generation through aldehyde oxidase and xanthine oxidase-associated oxidation, leading to accumulation of O2•?
aldehyde oxidase Binding (generation) of
1) Confidence 0.09 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2807457 Disease Relevance 1.13 Pain Relevance 0.11
It should be mentioned that i.t. pretreatment with RO-32-0432 significantly reversed the attenuation of morphine-induced rewarding effect following sciatic nerve ligation.
RO-32-0432 Binding (ligation) of in sciatic nerve associated with sciatic nerve and morphine
2) Confidence 0.01 Published 2004 Journal Neuroscience Section Abstract Doc Link 15099668 Disease Relevance 0.47 Pain Relevance 1.51

General Comments

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