INT118182

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Context Info
Confidence 0.44
First Reported 2004
Last Reported 2010
Negated 2
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.38
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Trpv5) transmembrane transport (Trpv5)
Anatomy Link Frequency
plasma 2
Trpv5 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
member 8 2 75.00 Quite High
Kinase C 1 66.08 Quite High
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 4 96.52 Very High Very High Very High
Volume Depletion And Dehydration 2 81.28 Quite High
Weight Gain 1 77.76 Quite High
Apoptosis 1 60.00 Quite High
Kidney Stones 16 5.00 Very Low Very Low Very Low
Body Weight 4 5.00 Very Low Very Low Very Low
Hematuria 1 5.00 Very Low Very Low Very Low
Hypercalcemia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our current data showed that HCTZ did not affect protein abundance of TRPV5 in high calcium diet and vitamin D-induced severe hypercalciuric rats, resulting in small reduction of urinary calcium excretion.
Neg (not) Regulation (affect) of Localization (abundance) of TRPV5
1) Confidence 0.44 Published 2010 Journal Journal of Korean Medical Science Section Body Doc Link PMC2923802 Disease Relevance 0.38 Pain Relevance 0
None of the 80K-H mutants altered the TRPV5 plasma membrane localization nor the association of 80K-H with TRPV5, suggesting that 80K-H has a direct effect on TRPV5 activity.
Neg (nor) Regulation (altered) of Localization (localization) of TRPV5 in plasma
2) Confidence 0.27 Published 2004 Journal J. Biol. Chem. Section Abstract Doc Link 15100231 Disease Relevance 0 Pain Relevance 0.11

General Comments

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