INT118201

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Context Info
Confidence 0.22
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Title
Documents 3
Total Number 3
Disease Relevance 3.41
Pain Relevance 1.99

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Itgam) nucleus (Itgam)
Anatomy Link Frequency
macrophage 1
autonomic 1
neutrophil 1
Itgam (Rattus norvegicus)
Pain Link Frequency Relevance Heat
intrathecal 5 99.82 Very High Very High Very High
Spinal cord 6 98.16 Very High Very High Very High
cytokine 8 95.76 Very High Very High Very High
Inflammation 20 95.40 Very High Very High Very High
Inflammatory response 1 94.96 High High
allodynia 5 93.40 High High
ischemia 4 92.56 High High
agonist 4 90.52 High High
Pain 5 89.60 High High
Lasting pain 1 65.64 Quite High
Disease Link Frequency Relevance Heat
Adhesions 3 100.00 Very High Very High Very High
Frailty 9 98.16 Very High Very High Very High
INFLAMMATION 17 95.40 Very High Very High Very High
Pancreatitis 2 95.08 Very High Very High Very High
Hemorrhagic Shock 3 93.96 High High
Neuropathic Pain 5 93.40 High High
Cv Unclassified Under Development 4 92.56 High High
Adult Respiratory Distress Syndrome 43 91.36 High High
Injury 20 88.64 High High
Lung Injury 22 83.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A role of microglia is suggested by the observation that intrathecal choline suppressed the gp120-induced expression of, cd11b, a macrophage/microglial activation marker.
Negative_regulation (suppressed) of cd11b in macrophage associated with intrathecal
1) Confidence 0.22 Published 2010 Journal Brain Behav. Immun. Section Abstract Doc Link 20353818 Disease Relevance 0.89 Pain Relevance 1.45
The mechanisms of action of hypertonic saline are increasingly well understood, and include inhibition of neutrophil adhesion molecule CD11b [5], reduced TNF-?
Negative_regulation (inhibition) of CD11b in neutrophil associated with adhesions
2) Confidence 0.08 Published 2008 Journal BMC Pulm Med Section Body Doc Link PMC2467400 Disease Relevance 1.46 Pain Relevance 0.12
Transient blockade of the CD11d/CD18 integrin reduces secondary damage after spinal cord injury, improving sensory, autonomic, and motor function.
Negative_regulation (blockade) of CD11d in autonomic associated with spinal cord
3) Confidence 0.04 Published 2004 Journal J. Neurosci. Section Title Doc Link 15102919 Disease Relevance 1.05 Pain Relevance 0.42

General Comments

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