INT118421

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Context Info
Confidence 0.42
First Reported 2004
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.81
Pain Relevance 0.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Ubb (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 1 91.80 High High
Enkephalin 1 86.32 High High
Opioid 3 84.80 Quite High
adenocard 1 84.56 Quite High
tolerance 2 75.52 Quite High
Endogenous opioid 1 73.56 Quite High
Hippocampus 6 52.16 Quite High
anesthesia 3 48.28 Quite Low
long-term potentiation 11 5.00 Very Low Very Low Very Low
Glutamate receptor 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 7 95.56 Very High Very High Very High
Coronary Artery Disease 1 91.80 High High
Aids-related Complex 70 89.12 High High
Frailty 1 77.92 Quite High
Body Weight 1 5.44 Low Low
Cognitive Disorder 14 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Stroke 1 5.00 Very Low Very Low Very Low
Myocardial Infarction 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Trolox did not attenuate MV-induced increases in diaphragmatic levels of ubiquitin-protein conjugation, polyubiquitin mRNA, and gene expression of proteasomal subunits (20S proteasome alpha-subunit 7, 14-kDa E2, and proteasome-activating complex PA28).
Gene_expression (expression) of polyubiquitin mRNA
1) Confidence 0.42 Published 2008 Journal Am. J. Physiol. Regul. Integr. Comp. Physiol. Section Abstract Doc Link 18321950 Disease Relevance 0.15 Pain Relevance 0
Delt D and HIT significantly reduced total polyubiquitin transcript expression, 2.1-fold and 1.4-fold, respectively, in ischemic tissue, while SWAP and DADLE did not differ from saline controls.
Gene_expression (expression) of polyubiquitin transcript
2) Confidence 0.23 Published 2004 Journal J. Gerontol. A Biol. Sci. Med. Sci. Section Abstract Doc Link 15123752 Disease Relevance 0.49 Pain Relevance 0.56
Data

were normalized with the geometric mean of the three normalization genes polyubiquitin, Cyclophilin,

Gene_expression (normalized) of polyubiquitin
3) Confidence 0.19 Published 2008 Journal Neural Plasticity Section Body Doc Link PMC2631155 Disease Relevance 0.17 Pain Relevance 0.03

General Comments

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