INT118436

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Context Info
Confidence 0.49
First Reported 2004
Last Reported 2010
Negated 2
Speculated 0
Reported most in Abstract
Documents 3
Total Number 4
Disease Relevance 2.19
Pain Relevance 0.53

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (TRPV6) transmembrane transport (TRPV6)
Anatomy Link Frequency
brain 1
TRPV6 (Homo sapiens)
Pain Link Frequency Relevance Heat
qutenza 4 97.12 Very High Very High Very High
imagery 13 93.20 High High
palliative 6 81.28 Quite High
Pain 1 75.24 Quite High
TRP channel 1 73.64 Quite High
Central nervous system 2 6.16 Low Low
medulla 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Malignant Neoplastic Disease 2 98.48 Very High Very High Very High
Disease 6 98.08 Very High Very High Very High
Metastasis 32 97.52 Very High Very High Very High
Neurilemmoma 14 97.48 Very High Very High Very High
Liver Cancer 2 96.16 Very High Very High Very High
Rheumatoid Arthritis 114 95.36 Very High Very High Very High
Stress 1 87.60 High High
Cancer 14 86.76 High High
Pain 1 75.24 Quite High
Acoustic Neuroma 4 58.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The dose to all OAR, low dose volume and Dmean of the healthy brain showed clearly better results for CAT.
Positive_regulation (results) of CAT in brain
1) Confidence 0.49 Published 2010 Journal Radiat Oncol Section Body Doc Link PMC2949676 Disease Relevance 0.78 Pain Relevance 0.12
Higher cumulative dose in GTV as result of CAT can be subordinated in treatment for malignant diseases like metastases, but should be considered for irradiation of benign targets, too.
Positive_regulation (result) of CAT associated with malignant neoplastic disease, disease and metastasis
2) Confidence 0.45 Published 2010 Journal Radiat Oncol Section Body Doc Link PMC2949676 Disease Relevance 1.07 Pain Relevance 0.08
These cells express the mRNA of TRPV1, TRPV2, TRPV3 and TRPV4 channels, but not those of TRPV5 and TRPV6.
Neg (not) Positive_regulation (those) of TRPV6
3) Confidence 0.44 Published 2004 Journal Cell Calcium Section Abstract Doc Link 15126053 Disease Relevance 0.26 Pain Relevance 0.21
With the exception of TRPV5 and TRPV6, TRPV channel subunits preferentially assemble into homomeric complexes.
Neg (exception) Positive_regulation (exception) of TRPV6
4) Confidence 0.42 Published 2005 Journal J. Cell. Sci. Section Abstract Doc Link 15713749 Disease Relevance 0.08 Pain Relevance 0.11

General Comments

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