INT118459

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Context Info
Confidence 0.43
First Reported 2004
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 0.25
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

anatomical structure formation involved in morphogenesis (Bmp7) extracellular space (Bmp7)
Anatomy Link Frequency
spine 1
fibroblast 1
Bmp7 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 4 100.00 Very High Very High Very High
Eae 1 62.16 Quite High
Substantia nigra 3 50.64 Quite High
spinal inflammation 2 50.00 Quite Low
Pain 2 25.00 Low Low
Inflammation 7 5.00 Very Low Very Low Very Low
metalloproteinase 7 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rotator Cuff Tears 3 84.64 Quite High
Disease 3 58.56 Quite High
Low Back Pain 2 56.40 Quite High
Calcification 2 53.28 Quite High
Pain 1 25.00 Low Low
Injury 17 5.00 Very Low Very Low Very Low
Osteoporosis 8 5.00 Very Low Very Low Very Low
INFLAMMATION 7 5.00 Very Low Very Low Very Low
Stress 5 5.00 Very Low Very Low Very Low
Hypercalcemia 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The present study was undertaken to investigate the effects of bone morphogenetic protein-7 (BMP-7), also named osteogenic protein-1 (OP-1), on the progression of a striatal 6-hydroxydopamine (6-OHDA) lesion.
Spec (investigate) Regulation (effects) of BMP-7
1) Confidence 0.43 Published 2004 Journal Brain Res. Section Abstract Doc Link 15126112 Disease Relevance 0 Pain Relevance 0.06
The changes in BMP-7 levels from baseline to after the follow-up period showed a significant correlation with the changes of BASRI-spine, but the changes in other BMPs did not show any significant relationship to the changes in clinical parameters.
Regulation (changes) of BMP-7 in spine
2) Confidence 0.14 Published 2008 Journal Scand. J. Rheumatol. Section Body Doc Link 18465455 Disease Relevance 0.11 Pain Relevance 0
In the present study, we evaluated the effect of the direct and simultaneous gene transfer of human BMP-2 and BMP-7 gene expression vectors (pCAGGS-BMP-2 and pCAGGS-BMP-7) on osteoinduction using in vivo electroporation.
Regulation (effect) of BMP-7
3) Confidence 0.07 Published 2006 Journal BMC Musculoskelet Disord Section Body Doc Link PMC1557501 Disease Relevance 0.05 Pain Relevance 0
The effect of various cytokines and osteoinductive growth factors, such as BMP-2, BMP-7, or rhBMP-12, TGF-beta1, TGF-beta2, TGF-beta3, and fibroblast growth factor, have been tested for TBI healing enhancement.
Regulation (effect) of BMP-7 in fibroblast associated with cytokine
4) Confidence 0.04 Published 2010 Journal J Orthop Surg Res Section Body Doc Link PMC2931497 Disease Relevance 0.08 Pain Relevance 0.10

General Comments

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