INT118463

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Context Info
Confidence 0.33
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.48
Pain Relevance 0.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Ptger2, Ptger1) signal transducer activity (Ptger2, Ptger1)
Anatomy Link Frequency
spinal 1
Ptger2 (Rattus norvegicus)
Ptger1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Spinal cord 5 98.00 Very High Very High Very High
spinal dorsal horn 2 95.64 Very High Very High Very High
Dorsal horn 2 92.40 High High
Hyperalgesia 3 86.68 High High
intrathecal 3 83.52 Quite High
antagonist 1 60.04 Quite High
withdrawal 1 54.36 Quite High
Pain 3 25.00 Low Low
nociceptor 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Nociception 4 92.44 High High
Hyperalgesia 3 86.68 High High
Ganglion Cysts 1 79.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The results of this study suggested that spinal PGE2 activates the EP1 receptors existing on the central terminals of primary afferents, subsequently increasing in [Ca2+]i in the spinal dorsal horn, which are involved in the mechanisms of spinal PGE2-induced nociceptive transmission.
PGE2 Positive_regulation (activates) of EP1 in spinal associated with nociception and spinal dorsal horn
1) Confidence 0.33 Published 2004 Journal Brain Res. Section Abstract Doc Link 15126118 Disease Relevance 0.48 Pain Relevance 0.74

General Comments

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