INT118515

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Context Info
Confidence 0.27
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.56
Pain Relevance 1.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PRKCA, TRPV1) plasma membrane (PRKCA, TRPV1) nucleoplasm (PRKCA)
transport (TRPV1) mitochondrion (PRKCA) small molecule metabolic process (PRKCA)
Anatomy Link Frequency
HEK 3
PRKCA (Homo sapiens)
TRPV1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Kinase C 6 100.00 Very High Very High Very High
qutenza 8 92.56 High High
agonist 5 92.40 High High
Thermal hyperalgesia 2 90.32 High High
Hyperalgesia 5 78.24 Quite High
substance P 1 67.28 Quite High
Calcitonin gene-related peptide 1 66.00 Quite High
Inflammation 2 63.36 Quite High
Dorsal horn 1 60.88 Quite High
Spinal cord 1 59.36 Quite High
Disease Link Frequency Relevance Heat
Hyperalgesia 7 90.32 High High
INFLAMMATION 2 63.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Activation of PAR2 or PKC induced phosphorylation of TRPV1 in HEK cells, suggesting a direct regulation of the channel.
Positive_regulation (Activation) of PKC in HEK Positive_regulation (induced) of Phosphorylation (phosphorylation) of TRPV1 in HEK associated with kinase c
1) Confidence 0.27 Published 2004 Journal J. Neurosci. Section Abstract Doc Link 15128844 Disease Relevance 0.56 Pain Relevance 1.58

General Comments

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