INT118545

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Context Info
Confidence 0.00
First Reported 2004
Last Reported 2004
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.09
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Agtr2, Msr1) cytosol (Msr1) signal transduction (Agtr2)
transcription factor binding (Agtr2) signal transducer activity (Agtr2)
Anatomy Link Frequency
spleen 1
Agtr2 (Mus musculus)
Msr1 (Mus musculus)
Pain Link Frequency Relevance Heat
Cannabinoid receptor 3 96.52 Very High Very High Very High
analgesia 1 87.36 High High
antagonist 2 75.00 Quite High
Disease Link Frequency Relevance Heat
Hypothermia 1 88.40 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
After oral administration, SR147778 displaced the ex vivo [3H]-CP 55,940 binding to mouse brain membranes (ED50 = 3.8 mg/kg) with a long duration of action, whereas it did not interact with the CB2 receptor expressed in the mouse spleen.
CB2 receptor Neg (not) Binding (interact) of SR147778 in spleen
1) Confidence 0.00 Published 2004 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 15131245 Disease Relevance 0.09 Pain Relevance 0.29

General Comments

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