INT118682

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Context Info
Confidence 0.67
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.25
Pain Relevance 1.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (KRIT1) protein complex (KRIT1)
Anatomy Link Frequency
PFCX 1
KRIT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
fluoxetine 14 99.72 Very High Very High Very High
antidepressant 4 94.92 High High
Hippocampus 2 82.36 Quite High
Desipramine 2 78.40 Quite High
imagery 33 5.00 Very Low Very Low Very Low
Spinal cord 3 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
magnetoencephalography 1 5.00 Very Low Very Low Very Low
nerve block 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cognitive Disorder 5 99.08 Very High Very High Very High
Fatigue 8 98.12 Very High Very High Very High
Urological Neuroanatomy 10 97.80 Very High Very High Very High
Stress 2 97.78 Very High Very High Very High
Toxicity 1 68.88 Quite High
Intellectual Impairment 1 11.96 Low Low
Stroke 21 5.00 Very Low Very Low Very Low
Coronary Artery Disease 15 5.00 Very Low Very Low Very Low
Frailty 6 5.00 Very Low Very Low Very Low
Paralysis 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
All drug treatments markedly increased the enzymatic activity of nuclear Ca2+/calmodulin (CaM) kinase IV (CaMKIV), a major neuronal CREB kinase, in PFCX.
Positive_regulation (increased) of CaM in PFCX associated with urological neuroanatomy
1) Confidence 0.67 Published 2004 Journal Neuropsychopharmacology Section Abstract Doc Link 15138445 Disease Relevance 0.43 Pain Relevance 0.70
Selective phosphorylation of nuclear CREB by fluoxetine is linked to activation of CaM kinase IV and MAP kinase cascades.
Positive_regulation (activation) of CaM associated with fluoxetine
2) Confidence 0.45 Published 2004 Journal Neuropsychopharmacology Section Title Doc Link 15138445 Disease Relevance 0.20 Pain Relevance 0.54
Consistently in the last decade, an important increase in the use of CAM has been observed in Europe, USA and Australia (2,4,5), in which most studies showed women as the major users of alternative medicines when compared with men (2,4,5).
Positive_regulation (increase) of CAM
3) Confidence 0.02 Published 2010 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Body Doc Link PMC2892351 Disease Relevance 0.07 Pain Relevance 0
A fourth area where BCI assistive technology can benefit from recent research is in the recognition of the user's mental states (mental workload, stress level, tiredness, attention level) and cognitive processes (awareness to errors made by the BCI), which could facilitate interaction and reduce the user's cognitive effort by making the BCI assistive device react to the user.
Positive_regulation (facilitate) of interaction associated with stress, cognitive disorder and fatigue
4) Confidence 0.01 Published 2010 Journal Frontiers in Neuroscience Section Body Doc Link PMC2944670 Disease Relevance 0.54 Pain Relevance 0

General Comments

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