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Context Info
Confidence 0.49
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.42
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Tlr4) plasma membrane (Tlr4) intracellular (Tlr4)
cytoplasm (Tlr4)
Anatomy Link Frequency
spinal nerve 2
Tlr4 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
allodynia 1 83.04 Quite High
Neuropathic pain 1 75.00 Quite High
Traumatic nerve injury 1 66.32 Quite High
wide dynamic range 1 65.52 Quite High
Lasting pain 2 63.48 Quite High
Peripheral nerve injury 1 61.60 Quite High
neuralgia 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Neuropathic Pain 2 83.04 Quite High
Hypersensitivity 1 76.00 Quite High
Nervous System Injury 3 66.32 Quite High
Pain 2 63.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The spinal lumbar mRNA expression of ITGAM, TLR4, and CD14 was upregulated at 4 h post surgery, CD14 peaked 4 days after spinal nerve transection while ITGAM and TLR4 continued to increase until day 14 and returned to almost normal levels by postoperative day 28.
Positive_regulation (upregulated) of Transcription (expression) of TLR4 in spinal nerve
1) Confidence 0.49 Published 2004 Journal Neurochem. Int. Section Abstract Doc Link 15145554 Disease Relevance 0.42 Pain Relevance 0.35

General Comments

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