INT118860

Context Info Confidence 0.01 First Reported 2004 Last Reported 2004 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.10 Pain Relevance 0.27

cytoplasm (MCC, STAT3) signal transduction (MCC, STAT3) nucleus (MCC, STAT3) plasma membrane (MCC, STAT3) nucleoplasm (STAT3) DNA binding (STAT3)

MCC (Homo sapiens) STAT3 (Homo sapiens)

Pain Link Frequency Relevance Heat enkephalin 1 94.68 Opioid receptor 2 93.20 kinase C 3 92.64

Disease Link Frequency Relevance Heat Bordatella Infection 1 97.88 Leukemia 1 25.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The constitutively active Galpha4QL mutant also induced STAT3 phosphorylations at these sites and promoted STAT3-dependent luciferase activity.

Galpha4QL mutant Positive_regulation (induced) of Phosphorylation (phosphorylations) of STAT3

1) Confidence 0.01 Published 2004 Journal Mol. Pharmacol. Section Abstract Doc Link 15155836 Disease Relevance 0.10 Pain Relevance 0.27

General Comments

This test has worked.