INT118955

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Context Info
Confidence 0.29
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.54
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (PCNA) nucleoplasm (PCNA) nucleolus (PCNA)
nucleus (PCNA) DNA binding (PCNA) transcription factor binding (PCNA)
PCNA (Homo sapiens)
Pain Link Frequency Relevance Heat
opiate 1 92.84 High High
Morphine 6 75.00 Quite High
Pyramidal cell 38 61.04 Quite High
Hippocampus 13 24.88 Low Low
Inflammation 7 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Eae 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Retinoblastoma 54 100.00 Very High Very High Very High
Cancer 7 94.32 High High
Tauopathy 66 90.68 High High
Disease 66 89.80 High High
Death 18 89.52 High High
Stress 6 59.12 Quite High
Sclerosis 6 53.88 Quite High
Infection 11 43.36 Quite Low
Alzheimer's Dementia 64 27.80 Quite Low
Cognitive Disorder 12 26.64 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To this end, we examined the expression of two endogenous cell cycle markers in relation to BrdU: proliferating cell nuclear antigen (PCNA) and phosphorylated histone H3 (pHisH3).
Phosphorylation (phosphorylated) of PCNA
1) Confidence 0.29 Published 2004 Journal J. Neurosci. Res. Section Abstract Doc Link 15160390 Disease Relevance 0 Pain Relevance 0.30
Various markers were increased, that is, CyclinD2, phosphorylated Retinoblastoma protein, proliferating cell nuclear antigen (PCNA), cyclin B1 [30].
Phosphorylation (phosphorylated) of PCNA associated with retinoblastoma
2) Confidence 0.11 Published 2010 Journal International Journal of Alzheimer's Disease Section Body Doc Link PMC2938448 Disease Relevance 0.58 Pain Relevance 0
PCNA and phosphorylated retinoblastoma protein (Figure 8A).
Phosphorylation (phosphorylated) of PCNA associated with retinoblastoma
3) Confidence 0.11 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2748684 Disease Relevance 0.31 Pain Relevance 0.03
The retinoblastoma (Rb) and lamin A/C proteins are phosphorylated by the cyclin-dependent kinases (Cdks) that control cell cycle progression.
Phosphorylation (phosphorylated) of cyclin associated with retinoblastoma
4) Confidence 0.03 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2936540 Disease Relevance 0.65 Pain Relevance 0

General Comments

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