INT118985

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Context Info
Confidence 0.53
First Reported 2004
Last Reported 2008
Negated 0
Speculated 1
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 1.01
Pain Relevance 1.00

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cellular_component (Mc1r)
Anatomy Link Frequency
skin 6
hair follicles 2
Mc1r (Rattus norvegicus)
Pain Link Frequency Relevance Heat
melanocortin 1 receptor 13 100.00 Very High Very High Very High
ischemia 2 50.00 Quite Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Body Weight 8 93.20 High High
Cytomegalovirus Infection 4 77.76 Quite High
Cv Unclassified Under Development 2 50.00 Quite Low
Reperfusion Injury 1 50.00 Quite Low
Injury 1 5.00 Very Low Very Low Very Low
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Successful transfection of ASP gene in skin and hair follicles, as well as downregulation of melanocortin-1 receptor (MC1R) and tyrosinase expression upon treatment, was confirmed using immunohistochemistry and Western blot analysis.
Negative_regulation (downregulation) of Gene_expression (expression) of MC1R in skin associated with melanocortin 1 receptor
1) Confidence 0.53 Published 2004 Journal Gene Ther. Section Abstract Doc Link 15164092 Disease Relevance 0.25 Pain Relevance 0.25
Western blotting analyses and immunohistochemistry were employed to determine expression of MC-1R and MC-3R.
Spec (determine) Negative_regulation (determine) of Spec (determine) Gene_expression (expression) of MC-1R
2) Confidence 0.39 Published 2008 Journal Transplant. Proc. Section Body Doc Link 18790174 Disease Relevance 0 Pain Relevance 0
Successful transfection of ASP gene in skin and hair follicles, as well as downregulation of melanocortin-1 receptor (MC1R) and tyrosinase expression upon treatment, was confirmed using immunohistochemistry and Western blot analysis.
Negative_regulation (downregulation) of Gene_expression (expression) of melanocortin-1 receptor in skin associated with melanocortin 1 receptor
3) Confidence 0.38 Published 2004 Journal Gene Ther. Section Abstract Doc Link 15164092 Disease Relevance 0.25 Pain Relevance 0.25
Successful transfection of ASP gene in skin and hair follicles, as well as downregulation of melanocortin-1 receptor (MC1R) and tyrosinase expression upon treatment, was confirmed using immunohistochemistry and Western blot analysis.
Negative_regulation (downregulation) of in hair follicles Gene_expression (expression) of MC1R in skin associated with melanocortin 1 receptor
4) Confidence 0.18 Published 2004 Journal Gene Ther. Section Abstract Doc Link 15164092 Disease Relevance 0.25 Pain Relevance 0.25
Successful transfection of ASP gene in skin and hair follicles, as well as downregulation of melanocortin-1 receptor (MC1R) and tyrosinase expression upon treatment, was confirmed using immunohistochemistry and Western blot analysis.
Negative_regulation (downregulation) of in hair follicles Gene_expression (expression) of melanocortin-1 receptor in skin associated with melanocortin 1 receptor
5) Confidence 0.13 Published 2004 Journal Gene Ther. Section Abstract Doc Link 15164092 Disease Relevance 0.25 Pain Relevance 0.25

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