INT119015

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Context Info
Confidence 0.27
First Reported 2004
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.65
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (CR2)
Anatomy Link Frequency
B cells 2
CR2 (Homo sapiens)
Pain Link Frequency Relevance Heat
medulla 1 89.64 High High
Inflammation 5 89.44 High High
headache 2 85.16 High High
cytokine 7 83.36 Quite High
rheumatoid arthritis 25 78.92 Quite High
chemokine 1 25.04 Quite Low
member 8 1 9.60 Low Low
methotrexate 13 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
spinal inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Epstein-barr Virus 12 100.00 Very High Very High Very High
Herpes Simplex Encephalitis 3 98.52 Very High Very High Very High
Herpes Simplex Virus 3 93.96 High High
INFLAMMATION 5 89.44 High High
Ataxia 1 86.36 High High
Tinnitus 1 85.92 High High
Vertigo 1 85.52 High High
Headache 2 85.16 High High
Fever 1 84.76 Quite High
Rheumatoid Arthritis 26 78.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A lack of this EBV receptor on transformed B cells was described as a reason for long-term EBV seronegativity [34], which explains the absence of CD21 from our cDNA library.
Negative_regulation (lack) of EBV receptor in B cells associated with epstein-barr virus
1) Confidence 0.27 Published 2006 Journal BMC Genomics Section Body Doc Link PMC1522023 Disease Relevance 0.30 Pain Relevance 0
CD19, CD20, CD21, CD22, CD35 receptors were found to be diminished.
Negative_regulation (diminished) of CD21
2) Confidence 0.23 Published 2004 Journal Acta Medica (Hradec Kralove) Section Abstract Doc Link 15168883 Disease Relevance 1.00 Pain Relevance 0.13
Second, B cells may be depleted by monoclonal antibodies that inhibit CD19, CD20, CD21, or CD22 B cell surface antigen.
Negative_regulation (inhibit) of CD21 in B cell
3) Confidence 0.14 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC2833972 Disease Relevance 0.35 Pain Relevance 0.24

General Comments

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