INT119106

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Context Info
Confidence 0.03
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.16
Pain Relevance 0.67

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (FCGR1A, TNF) plasma membrane (FCGR1A, TNF) extracellular space (TNF)
extracellular region (TNF) intracellular (TNF) extracellular matrix organization (TNF)
FCGR1A (Homo sapiens)
TNF (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 1 100.00 Very High Very High Very High
Etanercept 8 98.14 Very High Very High Very High
spinal inflammation 1 95.80 Very High Very High Very High
Arthritis 1 94.68 High High
rheumatoid arthritis 2 93.84 High High
psoriasis 5 84.80 Quite High
Disease Link Frequency Relevance Heat
Cancer 2 100.00 Very High Very High Very High
Necrosis 2 100.00 Very High Very High Very High
INFLAMMATION 1 100.00 Very High Very High Very High
Low Back Pain 1 95.80 Very High Very High Very High
Seronegative Spondarthritis 1 94.68 High High
Rheumatoid Arthritis 2 93.84 High High
Psoriasis 5 84.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Etanercept is a human fusion protein of the tumor necrosis factor receptor (TNFR) and the Fc region of IgG1 that binds to and presumably inhibits the pro-inflammatory and pro-proliferative activity of the tumor necrosis factor (TNF).
Negative_regulation (inhibits) of IgG1 Binding (activity) of TNF associated with necrosis, inflammation, cancer and etanercept
1) Confidence 0.03 Published 2004 Journal J Drugs Dermatol Section Abstract Doc Link 15176161 Disease Relevance 1.16 Pain Relevance 0.67

General Comments

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