INT119145

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Context Info
Confidence 0.13
First Reported 2004
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.47
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (RAC2) signal transduction (RAC2) nuclear envelope (RAC2)
plasma membrane (RAC2) intracellular (RAC2) GTPase activity (RAC2)
Anatomy Link Frequency
colon 1
RAC2 (Homo sapiens)
RAC2 - C16S (1)
Pain Link Frequency Relevance Heat
anesthesia 2 93.92 High High
cytokine 1 87.28 High High
peripheral neuropathy 1 5.00 Very Low Very Low Very Low
lancinating pain 1 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Clostridium Infection 2 97.88 Very High Very High Very High
Colon Cancer 1 97.64 Very High Very High Very High
Salmonella Infection 1 81.92 Quite High
Viral Infection 1 64.56 Quite High
Death 1 51.92 Quite High
Hemophagocytic Lymphohistiocytosis 2 41.12 Quite Low
Syndrome 21 38.12 Quite Low
General Immunology 1 36.60 Quite Low
Hepatitis 1 32.64 Quite Low
Congenital Anomalies 3 31.28 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It has been suggested that Rab5a participates in the active recruitment of Rac2 to phagolysosomes, which is important for the destruction of the bacterium [27].
Rac2 Binding (recruitment) of
1) Confidence 0.13 Published 2008 Journal Eur J Pediatr Section Body Doc Link PMC2413085 Disease Relevance 0.20 Pain Relevance 0.04
C16S toxin bound to high molecular weight proteins on the surface of human colon carcinoma HT-29 cells and was internalized, but not if the cells were pretreated with neuraminidase.
C16S toxin (C16S) Binding (bound) of in colon associated with colon cancer
2) Confidence 0.01 Published 2004 Journal Biochem. Biophys. Res. Commun. Section Abstract Doc Link 15178410 Disease Relevance 0.27 Pain Relevance 0.09

General Comments

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