INT119190

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Context Info
Confidence 0.01
First Reported 2004
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 2.60
Pain Relevance 0.73

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (HLA-DRB5) Golgi apparatus (HLA-DRB5) endoplasmic reticulum (HLA-DRB5)
plasma membrane (HLA-DRB5)
HLA-DRB5 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 10 82.44 Quite High
Inflammation 2 75.00 Quite High
cytokine 4 25.00 Low Low
COX2 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Apoptosis 15 100.00 Very High Very High Very High
Death 7 91.44 High High
Hepatocellular Cancer 1 87.04 High High
Stomach Cancer 7 81.40 Quite High
INFLAMMATION 5 75.00 Quite High
Cancer 2 69.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Forced NAG-1 expression significantly induced apoptosis and DR-4 and DR-5 expression.
Positive_regulation (induced) of Gene_expression (expression) of DR-5 associated with apoptosis
1) Confidence 0.01 Published 2004 Journal Carcinogenesis Section Abstract Doc Link 15180942 Disease Relevance 0.98 Pain Relevance 0.29
Moreover, temporal expressions of DR-4 and DR-5 induced by sulindac sulfide were similar to that of NAG-1.
Positive_regulation (induced) of Gene_expression (expressions) of DR-5
2) Confidence 0.01 Published 2004 Journal Carcinogenesis Section Abstract Doc Link 15180942 Disease Relevance 1.03 Pain Relevance 0.33
Sulindac sulfide caused apoptosis, and induced expression of DR-5 and NAG-1 in Hep3B cells.
Positive_regulation (induced) of Gene_expression (expression) of DR-5 associated with apoptosis
3) Confidence 0.01 Published 2006 Journal Apoptosis Section Abstract Doc Link 16699947 Disease Relevance 0.60 Pain Relevance 0.11

General Comments

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