INT119213

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Context Info
Confidence 0.42
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.06
Pain Relevance 0.88

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

GTPase activity (Gnai2) cytoplasm (Gnai2) signal transducer activity (Gnai2)
cell proliferation (Gnai2) cytosol (Gnai2) nucleus (Gnai2)
Anatomy Link Frequency
shell 1
Gnai2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
gABA 5 100.00 Very High Very High Very High
Nucleus accumbens 7 93.84 High High
Morphine 9 85.84 High High
Dopamine 1 78.44 Quite High
opiate 1 74.84 Quite High
dopamine receptor 2 70.48 Quite High
Disease Link Frequency Relevance Heat
Apoptosis 1 56.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Comparison of gene expression between the shell and core subregions of vehicle-treated rats revealed significantly higher relative abundance of GABA-A alpha1, Galphai2 and post-synaptic density protein 95 transcript (PSD-95) mRNA levels in the shell, whereas Ggamma2 and synuclein 1 were more abundant in the core of the NAc.
Positive_regulation (abundance) of Galphai2 in shell associated with nucleus accumbens and gaba
1) Confidence 0.42 Published 2004 Journal Neuroscience Section Abstract Doc Link 15183518 Disease Relevance 0.06 Pain Relevance 0.88

General Comments

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