INT119265

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Context Info
Confidence 0.01
First Reported 2004
Last Reported 2004
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.46
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (CREBBP, PPM1E) nucleus (CREBBP, PPM1E) nucleoplasm (CREBBP)
small molecule metabolic process (CREBBP) protein complex assembly (CREBBP) DNA binding (CREBBP)
CREBBP (Homo sapiens)
PPM1E (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 2 95.36 Very High Very High Very High
Disease Link Frequency Relevance Heat
INFLAMMATION 2 94.96 High High
Cytomegalovirus Infection 1 84.72 Quite High
Disease 2 80.12 Quite High
Aging 1 63.96 Quite High
Stress 1 62.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The IkappaBalpha super-repressor blocked the effect of p21 on all but one of the promoters, and the response to p21 was abrogated by the mutagenesis of an NFkappaB element. p21 inducibility of all the tested promoters and of the endogenous p21-responsive genes was strongly inhibited by adenoviral E1A protein and its deletion mutants that bind p300/CBP but not p21 or Rb.
CBP Neg (not) Binding (bind) of E1A protein
1) Confidence 0.01 Published 2004 Journal Cell Cycle Section Abstract Doc Link 15190207 Disease Relevance 0.46 Pain Relevance 0.17

General Comments

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