INT119319

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Context Info
Confidence 0.00
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.30
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

DNA binding (Rhox3h) cytoplasm (Atrn) pigmentation (Atrn)
extracellular space (Atrn) extracellular region (Atrn) plasma membrane (Atrn)
Anatomy Link Frequency
brain 1
Atrn (Rattus norvegicus)
Rhox3h (Mus musculus)
Pain Link Frequency Relevance Heat
sodium channel 2 97.40 Very High Very High Very High
Glutamate 2 95.78 Very High Very High Very High
Glutamate receptor 4 89.60 High High
agonist 1 88.00 High High
Analgesic 1 70.36 Quite High
Neuronal excitability 1 38.88 Quite Low
Disease Link Frequency Relevance Heat
Convulsion 3 87.20 High High
Neuroblastoma 1 87.20 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since the synaptic release of glutamate mainly depends upon the activation of membrane voltage-sensitive sodium channels (VSSCs), the nature of interactions between nefopam and these ionic channels was studied by evaluating the effects of nefopam on binding of 3H-batrachotoxinin, a specific ligand of the VSSCs in rat brain membrane preparations.
membrane Binding (binding) of 3H-batrachotoxinin in brain associated with glutamate and sodium channel
1) Confidence 0.00 Published 2004 Journal Brain Res. Section Abstract Doc Link 15193535 Disease Relevance 0.30 Pain Relevance 0.37

General Comments

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