INT119413

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Context Info
Confidence 0.10
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 2.48
Pain Relevance 1.70

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (SEMA6A) signal transduction (TNFRSF11A) plasma membrane (SEMA6A)
cytoskeleton organization (SEMA6A) cell-cell signaling (TNFRSF11A)
Anatomy Link Frequency
osteoblast 1
osteoclast 1
SEMA6A (Homo sapiens)
TNFRSF11A (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 24 97.16 Very High Very High Very High
Inflammation 4 93.76 High High
Dorsal horn 4 73.76 Quite High
Neurotransmitter 2 66.64 Quite High
Disease Link Frequency Relevance Heat
Osteoporosis 2 99.44 Very High Very High Very High
Pain 18 97.16 Very High Very High Very High
INFLAMMATION 4 93.76 High High
Neuropathic Pain 4 93.08 High High
Cancer 4 82.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Insight into the mechanisms of osteoblast and osteoclast activation, via receptor activator for nuclear factor KB (RANK) dependent and independent mechanisms and a re-evaluation of primary afferent terminals within bone have led to a suggestion that CIBP may be a mixture of inflammatory and neuropathic stimuli.
via Positive_regulation (activator) of RANK in osteoclast associated with pain, inflammation, neuropathic pain and osteoporosis
1) Confidence 0.10 Published 2004 Journal Palliat Med Section Abstract Doc Link 15198116 Disease Relevance 1.24 Pain Relevance 0.85
Insight into the mechanisms of osteoblast and osteoclast activation, via receptor activator for nuclear factor KB (RANK) dependent and independent mechanisms and a re-evaluation of primary afferent terminals within bone have led to a suggestion that CIBP may be a mixture of inflammatory and neuropathic stimuli.
via Positive_regulation (activator) of RANK in osteoblast associated with pain, inflammation, neuropathic pain and osteoporosis
2) Confidence 0.03 Published 2004 Journal Palliat Med Section Abstract Doc Link 15198116 Disease Relevance 1.24 Pain Relevance 0.85

General Comments

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