INT119429

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Context Info
Confidence 0.29
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.17
Pain Relevance 0.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Stmn1) cytosol (Stmn1) cytoskeleton (Stmn1)
intracellular (Stmn1) cytoplasm (Stmn1)
Anatomy Link Frequency
hypothalamus 1
Stmn1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dopamine 46 96.84 Very High Very High Very High
Morphine 5 88.12 High High
agonist 36 81.68 Quite High
Glutamate 9 5.00 Very Low Very Low Very Low
Neurotransmitter 7 5.00 Very Low Very Low Very Low
Central nervous system 6 5.00 Very Low Very Low Very Low
gABA 4 5.00 Very Low Very Low Very Low
Paracetamol 1 5.00 Very Low Very Low Very Low
Somatostatin 1 5.00 Very Low Very Low Very Low
GABAergic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aids-related Complex 1 97.62 Very High Very High Very High
Repression 1 70.72 Quite High
Disease 8 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low
Neurological Disease 2 5.00 Very Low Very Low Very Low
Schizophrenia 2 5.00 Very Low Very Low Very Low
Generalized Anxiety Disorder 2 5.00 Very Low Very Low Very Low
Parkinson's Disease 1 5.00 Very Low Very Low Very Low
Stress Incontinence 1 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Glial fibrillary acidic protein (Gfap) and activity-regulated cytoskeleton-associated protein (Arc) mRNA were upregulated, while growth associated protein (Gap43), clathrin heavy chain (Cltc), alpha-tubulin, Tau, and stathmin were downregulated.
Negative_regulation (downregulated) of stathmin associated with aids-related complex
1) Confidence 0.29 Published 2004 Journal Neuropsychopharmacology Section Abstract Doc Link 15199374 Disease Relevance 0.10 Pain Relevance 0.38
The decreases in Apo-14, stathmin 1, microtubule-associated protein tau, along with an increase in microtubule-associated protein 1A and spectrin alpha 2 (Table 1) suggests that DA may also have remodelling effects on the cytoskeleton of cells in the goldfish hypothalamus.
Negative_regulation (decreases) of stathmin 1 in hypothalamus associated with dopamine
2) Confidence 0.02 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2924890 Disease Relevance 0.07 Pain Relevance 0.25

General Comments

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