INT119435

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Context Info
Confidence 0.42
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.77
Pain Relevance 2.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Rgs7) plasma membrane (Rgs7) nucleus (Rgs7)
cytoplasm (Rgs7) signal transducer activity (Rgs7)
Anatomy Link Frequency
PAG 3
striatum 1
Rgs7 (Mus musculus)
Pain Link Frequency Relevance Heat
Thalamus 6 97.84 Very High Very High Very High
Opioid 8 97.24 Very High Very High Very High
Morphine 14 94.52 High High
Central grey 2 92.72 High High
Analgesic 2 68.48 Quite High
tolerance 4 67.80 Quite High
addiction 2 65.68 Quite High
Intracerebroventricular 2 65.32 Quite High
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 8 99.68 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In post-dependent mice, the increases in RGS-R7 and Gbeta5 mRNA still persisted in the PAG and striatum at 8 and 16 days after starting the chronic opioid treatment.
Negative_regulation (persisted) of Positive_regulation (increases) of RGS-R7 in PAG associated with urological neuroanatomy and opioid
1) Confidence 0.42 Published 2005 Journal Neuropsychopharmacology Section Abstract Doc Link 15199376 Disease Relevance 0.38 Pain Relevance 1.26
In post-dependent mice, the increases in RGS-R7 and Gbeta5 mRNA still persisted in the PAG and striatum at 8 and 16 days after starting the chronic opioid treatment.
Negative_regulation (persisted) of in striatum Positive_regulation (increases) of RGS-R7 in PAG associated with urological neuroanatomy and opioid
2) Confidence 0.14 Published 2005 Journal Neuropsychopharmacology Section Abstract Doc Link 15199376 Disease Relevance 0.38 Pain Relevance 1.26

General Comments

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